Training Program in Mental Health Research

描述（由申请人提供）：拟议的心理健康研究培训计划将为神经科学的博士生和博士后提供在国内和国际公认的教师实验室的综合培训经验。博士前培训项目建立在一个令人兴奋的，翻译相关的课程上，在研究生院的第一年和第二年教授，最近通过联合赞助的博士前早期T32培训计划机制获得了NIH的支持。博士后项目将汇集临床和基础科学研究人员的互补资源。拟议中的新培训项目将是西奈山第一个支持神经科学博士生研究培训的项目，在西奈山为临床和基础研究员提供博士后心理健康研究培训的方法上也是独一无二的。优秀的培训教师有一个共同的主题兴趣：了解特定神经回路的功能和可塑性如何影响神经发育和神经精神疾病，以及如何受到神经发育和神经精神疾病的影响。西奈山医学院的各种实验室机会充分利用了转化神经科学的特殊优势，特别是在发育神经生物学、神经精神疾病机制、认知神经科学、神经成像、信号转导以及突触和行为可塑性方面。在西奈山，神经系统在不同的模型系统中进行研究，从“简单”的无脊椎动物，如海蜗牛、果蝇或线虫，一直到复杂的脊椎动物，包括非人灵长类动物和人类。通过他们的课程，博士生预科生将在基础神经生物学和神经和精神疾病的病理生理学方面获得坚实的基础。博士后学员将从住院医师或奖学金项目（如精神病学）或完成博士或医学博士/博士学位后录取。他们将获得量身定制的教学和研究经验。研究导师的选择是在积极促进多学科综合研究的协作环境中进行的。培训计划鼓励那些研究经费直接集中于心理健康研究的教师导师的参与，同时不排除那些研究对我们寻求传授的跨学科培训至关重要的人。研究培训也将有一个教学的“正在进行的工作”组成部分，以促进这些重要的跨学科互动，磨练演讲技巧，并提高对道德问题的认识。采用这种方法，心理健康研究培训计划将为博士生和博士后提供指导和实验工具，在我们的培训教师的实验室中，在心理健康研究中启动成功，富有成效，独立的职业生涯。

DESCRIPTION (provided by applicant): The proposed Training Program in Mental Health Research will provide predoctoral and postdoctoral students in the Neurosciences with an integrated training experience in the laboratories of nationally and internationally recognized faculty. The predoctoral training program builds on an exciting, translationally relevant curriculum taught in years one and two of graduate school that has been recently awarded NIH support through the Jointly Sponsored Predoctoral Early Stage T32 Training Program mechanism. The postdoctoral program will draw together complementary pools of clinical and basic science fellows. The proposed new training program would be Mount Sinai's first to support research training for Ph.D. students in the Neurosciences, and would be unique at Mount Sinai in its approach to providing postdoctoral mental health research training to clinical and basic fellows. Outstanding training faculty share a common thematic interest: understanding how the function and plasticity of specific neural circuits impact, and are impacted by, neurodevelopmental and neuropsychiatric disease. Varied laboratory opportunities at Mount Sinai School of Medicine take advantage of particular strengths in translational neuroscience, notably in developmental neurobiology, mechanisms of neuropsychiatric disease, cognitive neuroscience, neuroimaging, signal transduction, and synaptic and behavioral plasticity. At Mount Sinai, the nervous system is studied in diverse model systems, from 'simple' invertebrates such as the sea snail Aplysia, the fruit fly, or the worm C. elegans, all the way to complex vertebrates including nonhuman primates and humans. Through their course work, predoctoral trainees will have received a solid foundation in basic neurobiology and the pathophysiology of neurological and psychiatric disease. Postdoctoral trainees will be admitted from residency or fellowship programs (e.g. Psychiatry), or following completion of Ph.D. or M.D./Ph.D. programs, and they will be offered a tailored didactic and research experience. Selection of a research mentor is made in a collaborative environment that actively promotes multidisciplinary, integrative research. The training program encourages participation of faculty mentors whose research grants directly focus on mental health research, while not excluding those whose research is critically important for the interdisciplinary training we seek to impart. Research training will also have a didactic 'work in progress' component, to foster these important interdisciplinary interactions, hone presentation skills, and improve awareness of ethical issues. Using this approach, the Training Program in Mental Health Research will provide predoctoral and postdoctoral students with the guidance and experimental tools, in the laboratories of our training faculty, to launch successful, productive, independent careers in mental health research.