Establishing a prioritized research agenda for nontuberculous mycobacterial infec

描述(由申请人提供)：本申请寻求对一个研讨会的部分支持(R13)，该研讨会旨在确定非结核分枝杆菌(NTM)感染引起的疾病的研究议程并确定其优先顺序。拟议的为期两天的研讨会由美国胸科学会(ATS)组织，并将在计划于2014年5月在加利福尼亚州圣地亚哥举行的ATS年度会议之前举行。非霍乱弧菌代表150多个不同物种，在许多地区，这些环境微生物对未感染艾滋病毒的个人造成的感染发生率正在增加。不幸的是，由于缺乏研究，我们对NTM感染的了解受到了极大的阻碍。ATS与美国传染病学会合作，发布了关于管理非传染性疾病感染的指南。然而，这些建议往往不是以证据为基础的，正如在2007年公布的前一份准则中所审查的那样，仍然有许多问题没有得到回答。ATS希望召开一次研讨会，以确定和确定非关税壁垒研究议程的优先次序，该议程将改善该领域的重点，并有望改善资助机会。我们建议的目标如下：1.制定并在2014年举办一次研讨会，以确定针对非传染性疾病感染的优先研究议程；2.在ATS期刊上发表研讨会的会议记录和建议；3.通过ATS网站、ATS主办的播客以及向全国30多个NTM支持团体分发文件，进一步传播研讨会的成果。具体目标将通过召集大约60名对NTM感染感兴趣和有专业知识的临床医生、科学家和患者代表以及这一调查领域以外的科学家来实现。

DESCRIPTION (provided by applicant): This application seeks partial support (R13) for a workshop aimed at defining and prioritizing a research agenda for disease caused by non-tuberculosis mycobacterial (NTM) infections. The proposed 2-day workshop is being organized by the American Thoracic Society (ATS) and will be held prior to the annual ATS conference planned for May 2014 in San Diego, CA. NTM represent over 150 different species and the incidence of infections in HIV uninfected individuals caused by these environmental organisms is increasing in many areas. Unfortunately, our understanding of NTM infections is greatly hampered by a lack of research. The ATS, in collaboration with the Infectious Diseases Society of America, has published guidelines on the management of NTM infections. However, the recommendations are often not evidence based and as reviewed in the previous guidelines published in 2007, there remain many unanswered questions. The ATS would like to convene a workshop to define and prioritize a NTM research agenda that will improve the field's focus and hopefully funding opportunities. We propose the following aims: 1. Develop and hold a workshop in 2014 to define a prioritized research agenda for NTM infections; 2. Publish the proceedings and recommendations of the workshop in an ATS journal; 3. Further disseminate the findings of the workshop through the ATS website, a podcast hosted by ATS, and through dissemination of the document to the over 30 NTM support groups across the country. The specific aims will be accomplished by bringing together approximately 60 clinicians, scientists and patient representatives with interest and expertise in NTM infections as well as scientists outside of this area of investigation.