Training the Next Generation of Mental Health Researchers

描述(申请人提供)：尽管基础神经科学和分子遗传学取得了巨大的进步，但由于缺乏训练有素的内科科学家将其应用于精神疾病的关键问题，这些知识在理解精神疾病的病理生理学和治疗机制方面的利用可能会受到阻碍。这项申请是对一个项目的竞争性更新，该项目寻求通过积极和协作的指导和有针对性的研究支持来增加心理健康领域基础和临床研究调查人员的数量和质量，并通过积极参与基础神经科学和临床行为研究的研究人员的合作参与和指导未来的受训人员来促进转化性研究的发展。具体地说，该计划为参与精神病学研究培训和活动提供支持，从PGY 1岁开始，一直持续到PGY 4，如果有指示，则持续到PGY-5/6岁。对研究住院医师的培训支持的分配是在竞争的基础上每年确定的。除了对个别受训人员的津贴支持外，该计划还提供内部资金，以支持常驻研究项目、专业旅行和方法论、统计学和研究伦理方面的正式课程工作。每个实习生都被分配了一名职业导师，该导师帮助他们确定研究导师，并就与职业发展相关的持续问题提供支持和建议。每年制定和审查个性化培训计划(ITP)，并在PGY 2制定研究项目，在PGY 3和4进行研究。结合正式课程和实践研究经验，强调网络和职业发展机会，以及临床和研究培训的成功整合。研究实习医生参加正在进行的研究相关期刊俱乐部，包括由加州大学圣地亚哥分校联合组织的“虚拟”期刊俱乐部，以及两个年度研究务虚会：一个是院系务虚会，邀请所有研究实习生和教职员工介绍他们最近的工作总结；另一个是跨机构研究务虚会，在加州大学圣地亚哥分校和加州大学旧金山分校之间轮流进行。还需要参加负责任的研究行为研讨会。该计划在促进独立研究科学家职业方面的成功将通过一系列主观和客观工具进行评估，这些工具旨在分析受训者在研究培训过程中态度、知识和技能的变化，以及他们进入研究奖学金的情况，以及他们随后提交的出版物和培训补助金的记录。特别强调了妇女和少数族裔受训人员在精神病学研究方面的职业发展。

DESCRIPTION (provided by applicant): Although dramatic advances have occurred in basic neuroscience and molecular genetics, the utilization of such knowledge in understanding the pathophysiology of mental illness and mechanisms of treatment may be hindered by a dearth of physician scientists trained to apply it to key problems of mental diseases. This application is a competitive renewal of a program that seeks to increase the number and quality of basic and clinical research investigators in mental health through proactive and collaborative mentorship and targeted research support and to facilitate the development of translational research through the collaborative involvement and mentorship of prospective trainees by researchers active in basic neuroscience and clinical behavioral research. Specifically, the program provides support for involvement in psychiatric research training and activity beginning in the PGY 1 year and continuing incrementally through the PGY 4 and, if indicated, in the PGY-5/6 years. The allocation of training support to research residents is determined annually on a competitive basis. In addition to stipend support of individual trainees, the program provides internal funding to support resident research projects, professional travel, and formal course work in methodology, statistics and research ethics. Each trainee is assigned a career mentor who assists them in identifying a research mentor and provides support and advice about ongoing issues related to career development. An individualized training plan (ITP) is developed and reviewed yearly, and a research project is developed in PGY 2 and conducted in PGY 3 & 4. In conjunction with formal coursework and hands-on research experience, networking and career development opportunities are emphasized, as is the successful integration of clinical and research training. Research residents participate in ongoing research related journal clubs, including a "Virtual" Journal Club that includes research residents from other California training sites, and is co-organized by UCSD, as well as in two annual research retreats: one, a Departmental retreat in which all research trainees and faculty are invited to present a summary of their recent work, and the other, an interinstitutional Research Retreat, rotating between UCSD and UCSF. Participation in a Workshop on Responsible Conduct of Research is also required. The success of the program in facilitating independent research scientist careers will be assessed through a series of subjective and objective instruments constructed to assay changes in attitudes, knowledge, and skills of the trainees in the course of their research training, and their entry into research fellowships, and their subsequent record of publication and training grant submissions. The career development of women and minority trainees in psychiatric research is specifically emphasized.