Administrative and Biostatistics Core

以下是俄亥俄州州立大学（OSU）核心C的目标：（1）培养经常和 通过提供基本信息， （2）在以下方面提供生物统计支持：（a）合作设计 （B）干扰变量的建模和 实验数据;（c）整合分析，以发现，训练和验证高维 数据;（d）探索性分析和直观显示数据，以澄清结论和发现线索;（e） 调查独特的统计方法，以直接解决困难的数据或设计问题;以及（f） 协助提供一个数据库，储存项目生物学结果的电子版; (3)定期（每年三次）为高级调查员及其 （4）招募外部审查委员会，并组织年度会议， OSU内部咨询委员会。外部咨询委员会成员应 审查所有实验结果，帮助确定调查的优先次序，审查合作的协调，以及 （5）组织一个内部咨询委员会， 俄勒冈州立大学的一个专家小组将就该计划的有效性和实验进展、研究和评估提供建议。 指导，技术方法，统计评估和行政效率;（7）提供 为研究者提供项目相关沟通的出版服务，其中包括 准备手稿，摘要和其他出版物，包括写作的总体进展 每年报告整个计划项目，提交给资助机构，NCI/NIH;（8） 提供全面的财政审查、会计和预算分析;（8）提供一个数据库， 项目记录的电子版本;（9）维护与本项目相关的网站;（10 作为该项目与新的制药公司合作伙伴Killai的主要联系人， Inc.和NCI项目官员 相关性（参见说明）： 该项目核心的主要目的是提供基本的总体行政管理 职能和生物统计学和其他统计支持的所有其他组成部分，这一计划项目。 这样将有助于对计划的工作采取顺利、精简的办法。 项目/施工现场（如果需要额外空间，请使用项目/施工现场）

The following are the objectives of Core C at The Ohio State University (OSU): (1) To foster frequent and relevant communications between all parties involved in the work through the provision of basic administrative services; (2) To provide biostatistics support in terms of (a) collaboration on design of experiments to ensure conclusive results; (b) modeling of nuisance variables and sensitivity analyses of experimental data; (c) integration of analyses for discovery, training, and validation of high dimensional data; (d) exploratory analyses and visual displays of data that clarify conclusions and uncover leads; (e) investigation of unique statistical methods to-directly address difficult data or design problems; and (f) assistance with the provision of a database housing an electronic version of the project biological results; (3) To organize regular (three times annually) technical meetings for the senior investigators and their laboratory members; (4) To recruit an External Review Committee and organize an annual meeting of this group and the OSU Internal Advisory Committee. The members of External Advisory Committee shall review all experimental findings, help prioritize investigations, review the coordination of collaborations, and evaluate concepts that emerge from the studies; (5) To organize an Internal Advisory Committee where a panel of experts at OSU shall advise on the program effectiveness and experimental progress, research directions, technical approaches, statistical evaluation, and administrative effectiveness; (7) To provide publication services to the investigators for project related communications where this includes the preparation of manuscripts, abstracts, and other publications, including the writing of an overall progress report annually for the entire program project, to be submitted to the funding agency, NCl/NIH; (8) To provide overall fiscal review, accounting, and budget analyses; (8) To provide a database housing an electronic version pf the project records; (9) To maintain a website in relation to this program project; (10 To serve as primary contact for the program project with a new pharmaceutical company partner, Eisai, Inc. and the NCI Program Officer. RELEVANCE (See instructions): The primary purposes of this core of the program project are to provide basic overall administrative functions and biostatististical and other statistical support to all other components of this program project. In this manner a smooth, streamlined approach to the work planned will be facilitated. PROJECT/PERFORIWANCE SITE(S) (if additional space is needed, use Project/