Investigating cortical plasticity and connectivity in people with chronic low back pain and controls using combined TMS_EEG

关于易患慢性腰痛的因素或有效治疗的基础变化知之甚少。被认为反映适应过程的大脑变化与慢性疼痛有关，但其对CLBP的贡献程度尚不清楚。通过测量CLBP患者大脑变化的适应性，我将确定他们是否与健康对照组不同，使他们更容易患上慢性疼痛，并与治疗反应有关。

Little is known about the factors that predispose the development of chronic low back pain or what changes underpin effective treatment. Brain changes, thought to reflect adaptive processes are associated with chronic pain, but the extent of their contribution to CLBP is unknown. By measuring the adaptability of brain changes in people with CLBP I will determine if they differ from healthy controls in a way that predisposes them to develop chronic pain and is related to treatment response.