Cell Biology Core

进化与理论免疫学中心（CETI）的细胞生物学核心（CBC）是 在第二阶段成立，Charies Cunningham博士被任命为主任。CBC成立于 满足新聘用的主要调查员的需要，并通过购置新的 当时获得的CETI建筑空间。第二阶段用COBRE资金购买的CBC设备项目 包括倒置Nikon Ti荧光显微镜、Microm HM 550低温恒温器和Attune声学 聚焦流式细胞仪核心还获得了非COBRE来源蔡司共焦 显微镜作为CBC第三阶段的第一个目标的一部分，进一步扩大CBC的能力， 显微镜设施的核心，尼康高分辨率彩色相机将购买尼康 荧光显微镜CBC的第二个目标是购买BD Biosciences FACSAria II细胞分选仪， 补充已经到位的流式细胞术功能。此外，还将聘请一名全职技术人员， 协助核心主任提供增强的显微镜和细胞分选功能，从而帮助 以实现CBC的目标。CBC的第三个目标是发展和提供所有必要的服务， 核心用户，以最大限度地提高他们获得校外资助和实现长期职业生涯的可能性 成功这包括将CBC纳入行政核心的指导委员会和CETI的 试点项目和豁免计划，包括对用户的相关指导。CBC的最终目标是 制定并实施一种商业模式，使CBC在年底前实现财务独立。 第三阶段。在第一年和第二年为广播公司配备了充分的人员和设备，并进行了外联活动之后， 计划，以增加CBC的用户基础，CBC将开始过渡到成本中立在第三年， 试点项目援助和豁免裁决。最后，感谢联合国妇女署的支持， 将继续提供额外的试点项目奖励和设备服务合同资金 到CBC第三阶段后，在CETI存在的第十六年到第二十年。一个全面的、 CBC的工作人员将为我们的调查人员提供必要的新资源，增加他们获得安全的可能性。 资金，从而实现IDEA计划的目标。

The Cell Biology Core (CBC) within the Center for Evolutionary and Theoretical Immunology (CETI) was established in Phase II with Dr. Charies Cunningham named as Director. The CBC was established in response to the needs of newly-hired principal investigators and was facilitated by the acquisition of new CETI building space acquired at that time. CBC equipment items purchased in Phase II with COBRE funds include an inverted Nikon Ti fluorescent microscope, a Microm HM550 cryostat, and an Attune acoustic focusing flow cytometer. The core has also acquired from non-COBRE sources a Zeiss confocal microscope. As part of the CBC's first aim in Phase III, to further expand the CBC's capabilities and improve the microscopy facilities of the core, a Nikon high-resolution color camera will be purchased for the Nikon fluorescent microscope. The CBC's second aim is to purchase a BD Biosciences FACSAria II Cell Sorter to complement the flow cytometry functions already in place. In addition, a full-time technician will be hired to assist the core director with providing both enhanced microscopy and cell-sorting functions, thereby helping to fulfill the aims of the CBC. The third aim of the CBC is to develop and provide all the services needed for core users to maximize their likelihood of securing extramural funding and achieving long-term career success. This includes integrating the CBC into the Administrative Core's steering committee and CETI's Pilot Project and Waiver programs, including associated mentoring for users. The CBC's final aim is to develop and implement a business model that will transition the CBC to financial independence by the end of Phase III. After fully staffing and equipping the CBC in years one and two, accompanied by an outreach program to increase the CBC's user base, the CBC will begin to transition to cost neutrality in year three with the assistance of pilot project and waiver awards. Finally, thanks to the support received from the UNM administration, additional pilot project awards and equipment service contract funds will continue to be made to the CBC post-Phase III, in years sixteen through twenty of CETI's existence. An expanded and fully staffed CBC will provide essential new resources for our investigators, increase their likelihood of securing funding, and thus fulfill the goals ofthe IDeA program.