Innate Cell Plasticity Conference-Society of Leukocyte Biology

描述（由申请人提供）：白细胞生物学学会（SLB）是领先的科学学会，专注于促进白细胞及其在急性和慢性疾病（从感染、心血管炎症、癌症到神经系统疾病）的病理生理学中的作用的研究。从历史上看，SLB年会吸引了来自学术界、工业界和医疗保健组织的多学科与会者。该计划包括邀请全体会议，主题演讲和研讨会发言人，以及从提交的摘要中选出的发言人，加上海报会议和特别节目。包括研究和临床试剂制造商和分销商以及科学出版商在内的商业参展商也参加了会议。为了证明SLB的科学卓越性， SLB年会，SLB年会的过去与会者和当前SLB成员包括诺贝尔奖获得者，学院成员和基础和转化白细胞生物学的世界领导者。2013年会议将继续这一卓越传统，将各级科学研究人员聚集在一个环境中，以最大限度地促进思想交流，促进研究合作，并继续以加快基础研究和转化研究的进展为目标。2013年年会的中心主题突出了关于先天白细胞表型/功能可塑性及其在急性和慢性炎症条件下的关键调节作用的更具先见之明的主题。为了更好地促进这一重要领域的科学交流和初级科学家的培训，该提案要求NIH支持2013年SLB年度科学会议，题为“先天细胞可塑性调节因子”，以允许参与者通过旅行奖励和分担费用获得更多的机会。具体目标1。提供一个有凝聚力的，合议和及时的论坛，介绍和讨论先天细胞可塑性调节的新概念，它的病理生理学意义和翻译应用。这些将包括（1）对新的先天白细胞亚群的最新理解，（2）先天细胞记忆、可塑性和转化/重编程的紧迫范例，（3）先天细胞与内皮/上皮细胞之间的整合串扰，（4）定义先天细胞微生物相互作用的新方法，和（5）先天细胞可塑性与包括感染、癌症、心血管疾病和衰老在内的病症的发病机制的翻译相关性。该计划将邀请该领域的领导者进行演讲，以及从全球实验室提交的摘要中选出的初级研究人员/学员进行口头和/或海报演示。会议将有来自学术、政府、临床和工业实验室的约350-400名与会者参加。具体目标2。为年轻的研究人员和学员提供机会，与其领域的顶级研究人员密切互动，并在海报和讲台/口头会议上展示他们的研究成果。将举办一个专门的职业发展讲习班以及关于赠款编写和出版的培训班，以促进有抱负的学生和初级调查员的培训和发展。将根据科学成绩向选定的与会者发放旅行奖励。本次会议的参与者人数较少，海报会议有充足的时间，为初级研究人员创造了一个学院式的学习环境，使他们能够与白细胞生物学领域的领先科学家进行严格的讨论。具体目标3。促进妇女、少数民族和残疾科学家参与白细胞生物学这一重要的生物医学领域。将举办一个专门论坛，重点讨论妇女和少数民族科学家面临的障碍。将组织建立联系和专业职业发展讲习班，以解决职业发展的障碍和机会。

DESCRIPTION (provided by applicant): The Society for Leukocyte Biology (SLB) is the leading scientific society with a focus on facilitating research on leukocytes and their roles in te patho-physiology of both acute and chronic diseases ranging from infection, cardiovascular inflammation, cancer, to neurological diseases. Historically, the SLB annual meetings draw multi-disciplinary attendees from academia, industry, and health care organizations. The program consists of invited plenary, keynote and symposium speakers, as well as speakers selected from submitted abstracts, plus poster sessions and special programs. Commercial exhibitors including manufacturers and distributors of research and clinical reagents and scientific publishers also attend the conference. To attest to the scientific excellence of SLB and SLB annual meetings, past attendees of SLB annual meetings and current SLB members include Nobel Laureates, Academy members, and world leaders in basic and translational leukocyte biology. The 2013 meeting will continue this tradition of excellence by bringing together scientific researchers of all levels in an environment geared to maximize interactions for the exchange of ideas, foster research collaborations, with the continued goal of accelerating progress in basic and translational research. The central theme of the 2013 annual meeting highlights the more prescient topics concerning innate leukocyte phenotypic/functional plasticity and their key modulatory roles in both acute and chronic inflammatory conditions. To best facilitate scientific exchange and training of junior scientists in this important area, this propoal requests NIH support for the 2013 SLB annual scientific conference entitled "Regulators of Innate Cell Plasticity" to allow greater access for participants via travel awards and shared costs. Specific Aim 1. To provide a cohesive, collegial and timely forum for presentation and discussion of emerging concepts in the regulation of innate cell plasticity, it's patho-physiologicl significance and translational application. These will include (1) most updated understandings of novel innate leukocyte subsets, (2) pressing paradigms of innate cell memory, plasticity and conversion/reprogramming, (3) integrated cross-talk among innate cells with endothelial/epithelial cells, (4) novel approaches in defining innate cell microbial interactions, and (5) the translational relevance of innate cell plasticity to the pathogenesis of conditions tha include infection, cancer, cardiovascular disease and aging. The program will feature invited presentations from leaders in the field, as well as oral and/or poster presentations by junior investigators/ trainees selected from among the abstracts submitted by laboratories worldwide. The meeting will target approximately 350-400 participants from academic, governmental, clinical and industrial laboratories. Specific Aim 2. To provide an opportunity for young investigators and trainees to interact closely with top echelon, well-established researchers in their fields, and to present their research findings in both poster and podium/oral sessions. A dedicated career development workshop as well as training session on grant writing and publication will be held to foster the training and development of aspiring students and junior investigators. Travel awards will be administered to selected participants based on scientific merits. The smaller number of participants and ample time for the poster sessions at this meeting creates a collegial learning environment for junior investigators to engage in rigorous discussion with the leading scientists in the area of leukocyte biology. Specific Aim 3. To foster the participation of women, minority, and disabled scientists in the important biomedical field of leukocyte biology. A specific forum focusing on obstacles facing women and minority scientists will be held. Networking and professional career development workshops will be organized to address obstacles and opportunities for career development.