Center for Environmental Health Sciences

描述(由申请人提供)：本申请请求Cobre继续支持环境健康科学中心(CEHS)，该中心成立于2000年，目的是开发一个具有国家竞争力的跨学科研究计划，研究人类疾病的机制和环境对这些疾病的影响。科布雷I奖和科布雷II奖(分别为2002年和2007年)通过CEHS的支持加强了该机构的生物医学研究基础设施，并增强了研究人员独立竞争外部同行审查支持的能力。聘用和指导了教员，建立了设施核心，支持了研究项目，导致CEHS调查人员的外部赠款资金和出版物大幅增长。蒙大拿大学为这一成功作出了重大贡献，提供了财政支持和大量新的研究空间。已经制定了一项战略计划，通过以下目标将CEHS转变为一个可持续的长期中心：目标1：鼓励和促进合作研究，以实现研究方案和核心的可持续性。这一目标将通过战略计划来实现，该战略计划将继续培养CEHS调查员，预测和瞄准研究机会，提出强有力的建议，并建立一个高效和互动的设施核心。目标2：利用试点赠款计划、培训机会和外部专门知识，在CEHS资助的研究组合的基础上再接再厉。试点项目计划将用于资助最有希望的研究，将在竞争的基础上提供培训机会，以支持调查人员的继续教育机会，外部专业知识(外部咨询委员会和特邀专家)将提供科学指导。目标3：提供领导和行政支持，并继续评估和完善中心和核心业务。领导和行政支助将为促进调查员的研究成功提供关键的基础设施，评估将用于确定有效性。目标4：利用蒙大拿大学的承诺，利用科布雷的支持来实现中心长期可持续发展的目标。

DESCRIPTION (provided by applicant): This application requests continuance of COBRE support for the Center for Environmental Health Science (CEHS) which was established in 2000 with the goal of developing a nationally competitive interdisciplinary research program to study the mechanisms of human disease and environmental impacts on those diseases. The COBRE I and II awards (2002 and 2007, respectively) strengthened the institution's biomedical research infrastructure through the support of the CEHS and enhanced the ability of investigators to compete independently for external peer-reviewed support. Faculty were hired and mentored, Facility Cores were established, and research projects were supported resulting in substantial growth of external grant funding and publications from CEHS investigators. The University of Montana contributed significantly to the success with financial support and substantial new research space. A strategic plan has been established to transition CEHS into a sustained long-term center through the following aims: Aim 1: Encourage and facilitate collaborative research to achieve sustainability of the research program and cores. This Aim will be accomplished through the Strategic Plan to continue to develop CEHS investigators, anticipate and target research opportunities with strong proposals and a highly effective and interactive Facility Cores. Aim 2: Utilize the pilot grant program, training opportunities and external expertise to build on the CEHS funded research portfolio. The pilot project program will be used to fund the most promising research, training opportunities will be provided on a competitive basis to support continued education opportunities to investigators, and external expertise (External Advisory Committee and invited experts) will provide scientific guidance. Aim 3: Provide leadership and administrative support and continue to evaluate and refine center and core operations. Leadership and administrative support will provide critical infrastructure to facilitat investigator's research success and evaluation will be used to determine effectiveness. Aim 4: Utilize the University of Montana commitment to leverage the COBRE support to achieve the goal of long-term center sustainability.