19th Hemoglobin Switching Conference

描述（由申请人提供）： 一年两次的血红蛋白转换会议已经持续了37年，其巨大的成功有多种原因。首先，组织者（Stamatoyannopoulos，Higgs和Engel）努力识别并强调新发现，始终包括影响血红蛋白转换过程的新调查人员和研究。第二，这是唯一的场地（除了年度ASH会议，有超过14，000名与会者），汇集了基础科学家和临床医生，讨论血红蛋白病的分子和发育起源以及治疗方法。第三，这些会议在历史上已经演变成关注科学所引导的任何领域，因此仍然非常热门，并且不仅是展示第一个cDNA克隆，第一个克隆的人类基因组位点的论坛（和第一个突变相同），促红细胞生成素的结构，但它也推出了许多目前在这一领域的领导者的职业生涯（事实上，许多博士后研究员和年轻的教师在这次会议的全体会议上首次介绍了他们的工作）。第四，这是关于这个话题的唯一一次会议，通常有来自美国内外的调查人员参加，这一事实反映在美国和欧洲每年两次的地点交替上。2014年，会议将再次在英国牛津大学圣约翰学院举行，因为国际交通便利和经济实惠。

DESCRIPTION (provided by applicant): The biannual Hemoglobin Switching Conference has been ongoing for 37 years, and there are multiple reasons for its resounding success. First and foremost, the organizers (Stamatoyannopoulos, Higgs and Engel) strive to identify and then highlight new discoveries by always including new investigators and studies that impinge on the process of hemoglobin switching. Second, this is the only venue (other than the annual ASH meeting, with more than 14,000 attendees) that brings together basic scientists and clinicians to discuss both the molecular and developmental origins of, and treatments for, hemoglobinopathies. Third, the meetings have historically morphed into focusing on wherever the science led, thus remaining extremely topical, and has not only been the forum for presenting the first cDNA clones, the first cloned human genomic locus (and the first mutations in same), the structure of erythropoietin, but it has also launched the careers of many of the current leaders in this field (indeed, numerous postdoctoral fellows and young faculty first presented their work in plenary sessions at this conference). Fourth, this is the only meeting on this topic that routinely has approximatel equal attendance by investigators from both inside and outside the U.S., and this fact is reflected by the bi-annual alternation in site between the U.S. and Europe. In 2014 the Conference will again be held at St. Johns College at Oxford University in Oxford, England, because of both international accessibility and economy.