Associate Professor of Neurology and Psychiatry

项目SuIVIMARY(请参阅说明)： 该计划的临床核心项目赠款将对参与该计划项目赠款(PPG)的所有受试者进行认知和临床评估。临床核心将招募和评估轻度认知障碍(MCI)的受试者，并将继续跟踪现有的正常健康对照受试者。中心将审查潜在受试者的研究方案，并获得完全知情同意，执行方案所需的认知、临床和神经学评估。后续预约和与受试者的持续电话联系将通过核心协调。临床核心将与ADRC和老龄化研究协调，以确保准确和及时地将临床信息、认知分数和其他与PPG数据集相关的数据传输到成像、方法学和统计(IMS)核心，以进行数据分析并与PIB PET和成像数据进行关联。PPG协调委员会由临床核心、行政核心、IMS核心和3个项目的PIS和共同信息系统的PIS组成，PPG管理员将监督临床核心。核心的所有调查人员以及他们为实现核心的目标而与之互动的所有个人多年来一直在一起工作，这进一步确保了拟议的工作将得到适当的开展。

PROJECT SUIVIMARY (See instructions): The Clinical Core of the Program Project Grant will perform the cognitive and clinical assessments for all subjects taking part in the Program Project Grant (PPG). The Clinical Core will recruit and assess subjects with Mild Cognitive Impairment (MCI) and will continue to follow existing Normal Healthy Control Subjects. The Core will review the study protocols with potential subjects and obtain full informed consent, perform cognitive, clinical and neurological assessments necessary for the protocol. Follow-up appointments and ongoing telephone contact with subjects will be coordinated through the Core. The Clinical Core will coordinate with the ADRC and the Aging Study to ensure accurate and timely transfer of clinical information, cognitive scores and other data relevant to the PPG dataset and subsequently to the Imaging, Methodology and Statistics (IMS) Core for data analysis and correlation with PIB PET and imaging data. The PPG Coordinating Committee comprising the Pis of the Clinical Core, Administrative Core, IMS Core, and Pis and Co-Is of the 3 projects and the PPG Administrator will oversee the Clinical Core. All of the Investigators in the Core and all of the individuals with whom they interact to achieve the aims of this Core have worked together for many years, adding to the assurance that the proposed work will be carried out appropriately.