1st International Thumb Osteoarthritis Workshop (ITOW)

描述（由申请人提供）：本R13提案的目的是为预定于2013年10月25日至26日在罗德岛纽波特举行的拇指腕骨关节炎（CMC）首届研讨会寻求部分支持。研讨会将汇集来自多个学科的临床医生和基础研究人员，参与与拇指CMC OA相关的研究，为跨学科交流有关该病的病因、发病机制、治疗和临床结果的信息提供一个论坛。拇指骨性关节炎是一种广泛存在的致残疾病，影响了21%的40岁以上人群和三分之二的55岁以上女性。拇指疼痛、无力和灵巧性丧失导致手部和上肢功能丧失。CMC OA的具体方面可能会在其他专业会议（如美国生物力学学会[ASB]，骨科研究学会[ORS]，国际骨关节炎研究学会[OARSI]和美国手部外科学会[ASSH]）上讨论，但目前还没有专门针对该疾病的集中、综合会议。会议的目标是介绍当前的知识状况，同时也介绍有可能影响治疗和临床结果的创新研究。研讨会将包括三个内容领域：与会者的讲台演讲、主题演讲和小组讨论。跨学科的交流和潜在的合作安排将从会议计划的单一会议形式、开放的小组讨论和参与的社交活动中产生，这将为与会者提供更多的见面机会。目标受众将包括从事CMC OA各个方面工作的基础科学家和临床医生，包括解剖学家、生物力学家、软骨生物学家、神经科学家、手外科医生和风湿病学家。将特别强调对学生和早期职业研究者的指导。会议组织者将汇总一份总结会议结果的共识论文，并与会议摘要一起发表在《手腕外科杂志》上。

DESCRIPTION (provided by applicant): The purpose of this R13 proposal is to seek partial support for an inaugural workshop on thumb carpometacarpal (CMC) osteoarthritis (OA), scheduled for October 25-26, 2013 in Newport, Rhode Island. The workshop will bring together clinicians and basic researchers from multiple disciplines involved in research relevant to thumb CMC OA, providing a forum for the cross-discipline exchange of information regarding the etiology, pathogenesis, treatment and clinical outcome of the disease. Thumb CMC OA is a widespread, disabling disease that affects 21% of people over the age of 40, and two-thirds of women over the age of 55. Thumb pain, weakness, and loss of dexterity lead to disabling impairment in hand and upper extremity function. Specific aspects of CMC OA may be covered at other specialty meetings (such as the American Society of Biomechanics [ASB], the Orthopaedic Research Society [ORS], the Osteoarthritis Research Society International [OARSI], and the American Society for Surgery of the Hand [ASSH]), but there is currently no focused, integrative meeting designed to address the disease specifically. The goal is to include presentations on the current state of knowledge, but also on innovative research that has the potential to influence treatment and clinical outcomes. The workshop will include three content areas: attendee podium presentations, keynote presentations, and panel discussions. Cross-discipline communication and potential collaborative arrangements will emanate from the single-session format of the meeting program, the open panel discussions, and engaging social events, which will give the attendees additional opportunities to meet. The target audience will include basic scientists and clinicians who work on all aspects of CMC OA, including anatomists, biomechanists, cartilage biologists, neuroscientists, hand surgeons and rheumatologists. Special emphasis will be placed on mentoring of students and early-career investigators. A consensus paper summarizing the meeting findings will be assembled by the meeting organizers and published alongside the meeting abstracts in the Journal of Wrist Surgery.