Immunology and Infectious Diseases

描述(申请人提供)：所在部门哈佛大学公共卫生学院(HSPH)生物科学系(DBS)免疫学和传染病系(DID)由一支强大的科学家团队组成，他们致力于研究与免疫反应以及传染病的生物学、流行病学和免疫学有关的问题。DBS成立于1993年，是一个伞形结构，涵盖免疫学和传染病、复杂疾病遗传学、癌细胞生物学、环境卫生和营养学等领域的生物实验室科学。公共卫生中的生物科学(BPH)博士课程位于HSPH，由艺术与科学研究生院提供。这项博士前培训补助金竞争性续签申请将支持选择在免疫学和传染病系教员实验室工作的BPH学生。良性前列腺增生症项目提供了一个独特的机会，可以培训一批在各个生物研究领域拥有专门知识并具有广泛的流行病学和生物统计学跨学科知识的领导干部。越来越明显的是，流行病学家和实验室科学家之间的密切互动以最佳方式促进了疾病预防方面的进展，实验室发现和流行病学观察以迭代的方式相互作用，以促进这两个领域的研究。我们在这一资助期间的培训记录一直很好，这一点从我们支持的博士前学生的出版记录和职业道路上得到了证明。该部门。可以细分为三大领域，免疫学、寄生虫和其他感染的分子生物学和病毒学。这些部门的教员包括：PI，Laurie Glimcher，淋巴细胞基因表达；Barry Bloom，Sarah Fortune和Eric Rubin，结核病；Tiffany Horng，炎症，Wendy Garrett，宿主-共生相互作用；Dyann Wirth，疟疾，利什曼病；Barbara Burleigh，T.ruzi，疟疾；Manoj Duraisingh，疟疾；Myron Essex，Phyllis Kanki，人类免疫缺陷病毒。HMS的三名主要教员是朱迪·利伯曼和约瑟夫·索德罗斯基，艾滋病毒，L-何，细胞因子和Hidde Ploegh，麻省理工学院，病毒感染细胞生物学。 相关性(见说明)：基本的生物学和流行病学发现必须放在广泛的社会背景中。该计划鼓励在实验室研究和实地工作之间建立更紧密的联系方面具有互补利益的科学家之间的积极合作-所有这些都着眼于开发创新的预防方法。免疫学和传染病领域的学生，以及HSPH免疫和传染病系的研究生是这种互动的理想选择。

DESCRIPTION (provided by applicant): The Dept. of Immunology and Infectious Diseases (DIID) in the Division of Biologic Sciences (DBS) at the Harvard School of Public Health (HSPH) comprises a strong team of accomplished scientists who work on problems related to the immune response and to the biology, epidemiology and immunology of infectious diseases. DBS, established in 1993, is an umbrella structure that encompasses the biologic laboratory sciences in the areas of Immunology and Infectious Diseases, the Genetics of Complex Diseases, Cancer Cell Biology, Environmental Health, and Nutrition. The Ph.D. Program in Biological Sciences in Public Health (BPH) is located at HSPH and is offered by the Graduate School of Arts and Sciences. This predoctoral training grant competitive renewal application would support BPH students who choose to work in laboratories of faculty members of the Department of Immunology and Infectious Diseases. The BPH program provides a unique opportunity for training a cadre of leaders who possess expertise in the individual fields of biological research and a broad interdisciplinary knowledge of epidemiology and biostatistics. It has become increasingly evident that progress in disease prevention is optimally promoted by a close interaction between epidemiologists and laboratory scientists, where laboratory discoveries and epidemiological observations interact in an iterative manner to advance research in both fields. Our training record in this grant period has been excellent as evidenced by the publication record and career paths of the predoctoral students supported. The Dept. can be subdivided into three major areas, Immunology, Molecular Biology of Parasitic and Other Infections, and Virology. Faculty members in these Divisions are the PI, Laurie Glimcher, gene expression in lymphocytes; Barry Bloom, Sarah Fortune and Eric Rubin, tuberculosis; Tiffany Horng, inflammation, Wendy Garrett, host-commensal interactions; Dyann Wirth, malaria, leishmaniasis; Barbara Burleigh, T. cruzi, malaria; Manoj Duraisingh, malaria; Myron Essex, Phyllis Kanki, human immunodeficiency virus. Three faculty members with primary appointments at HMS are Judy Lieberman and Joseph Sodrowski, HIV, l-Cheng Ho, cytokines and Hidde Ploegh, MIT, cell biology of viral infections. RELEVANCE (See instructions): Basic biological and epidemiological discoveries must be placed in a wide social context. This program encourages active collaboration among scientists who share complementary interests in developing closer linkages between laboratory research and field work- all with an eye to developing innovative approaches to prevention. The field of immunology and infectious diseases, and the graduate students in the Department of Immunology and Infectious Diseases at HSPH is ideally suited for this Interaction.