Mentoring Researchers in Aging in Vulnerable Populations

 描述（由申请人提供）：该提案的目的是1）发展候选人的能力和专业知识，作为研究弱势成年人老龄化的初级研究人员的导师; 2）对无家可归的老年人的患病率，风险因素和老年疾病的后果进行以患者为导向的研究; 3）对无家可归的老年人的管理和限制症状的后果进行以患者为导向的研究，4）使用候选人的研究作为指导弱势群体老龄化的初级研究人员的平台。候选人是一名在学术安全网医院执业的普通内科医生，他建立了一个具有高影响力，资金充足的独立临床研究项目，并拥有出色的出版记录。在完成她的普通内科奖学金后的13年里，她已经成为学员的成功导师，他们发表了高影响力的研究，成功获得资助，并继续参与以患者为导向的研究。候选人已经开发了一个广泛的研究组合，重点是弱势群体的健康结果。作为第一批确定无家可归人口老龄化的研究人员之一，该候选人获得了NIA的R 01资助，以研究50岁及以上无家可归成年人的生命历程事件与老年疾病发展之间的相互作用。她迄今为止的工作影响了关键干预措施的发展和扩大，以解决无家可归人口的健康问题，包括支持性住房和临时护理。该提案将为候选人提供受保护的时间，以增加她的专业知识，扩大她的指导计划，并开发新的研究，重点是限制无家可归的老年人的症状，以指导干预措施的发展，以改善精神病学，减少对急诊科的依赖。除了获得老龄化研究方法的新专业知识外，候选人还将制定一个正式的指导计划，计划招募，选拔，发展和评估将成为以患者为导向的研究领导者的学员。她将与每个学员合作，建立一个有重点的职业发展计划，他们在其中完成研究项目，并发展成为独立调查员所需的技能。这些计划将充分利用UCSF出色的临床研究培训环境。她将利用她在UCSF的领导地位，招募更多对弱势群体老龄化问题研究感兴趣的学员。

 DESCRIPTION (provided by applicant): The aims of this proposal are to 1) develop the candidate's capacity for and expertise in serving as a mentor to junior investigators studying aging in vulnerable adults; 2) perform patient oriented research on the prevalence, risk factors for and consequences of geriatric conditions in older homeless adults; 3) perform patient oriented research on the management and consequences of limiting symptoms in older homeless adults and 4) use the candidate's research as a platform for mentoring junior investigators in aging in vulnerable populations. The candidate, a General Internist who practices at an academic safety-net hospital, has established a high-impact, well-funded independent clinical research program with an outstanding publication record. In the 13 years since completing her General Internal Medicine fellowship, she has established herself as a successful mentor of trainees who have published high-impact research, become successfully funded, and continue to participate in patient-oriented research. The candidate has developed an extensive research portfolio focused on the health outcomes of vulnerable populations. As one of the first researchers to identify the aging of the homeless population, the candidate received R01 funding from the NIA to examine the interaction between life course events and the development of geriatric conditions in homeless adults aged 50 and older. Her work to date has influenced the development and expansion of key interventions to address the health of homeless populations, including supportive housing and respite care. This proposal will provide the candidate with protected time to increase her expertise, expand her mentoring program and develop new research focused on limiting symptoms in older homeless adults in order to guide the development of interventions to improve symptomatology and reduce reliance on the Emergency Department. In addition to gaining new expertise in aging research methods, the candidate will develop a formal mentoring program with plans for the recruitment, selection, development, and evaluation of mentees who will become leaders in patient-oriented research focused on aging vulnerable populations. She will work with each mentee to establish a focused career development plan in which they complete research projects and develop the skills needed to become independent investigators. These plans will make full use of the outstanding clinical research training environment at UCSF. She will leverage her leadership positions at UCSF to recruit more mentees interested in research on aging issues in vulnerable populations.