Cincinnati Regional Coordinating Stroke Center (Cincinnati RCC)

描述（由申请人提供）：拟议的NINDS卒中临床试验网络（NSTN）的目标是利用多学科卒中专业知识协同有效地设计和执行卒中临床试验的所有阶段。我们将作为NSTN的区域协调中心（RCC），将一个全面整合的临床试验网络方法更广泛和更有凝聚力地用于脑卒中。我们的目标是：(1)有效地实施试验，招募和留住参与者，并作为RCC优化数据质量；(2)作为经验丰富的科学家、临床医生、试验人员和协调员积极参与NSTN；(3)成功培训

DESCRIPTION (provided by applicant): The objectives of the proposed NINDS Stroke Clinical Trials Network (NSTN) are to harness multidisciplinary stroke expertise to collaboratively and efficiently design and execute stroke clinical trials in all phases. We will bring a fully integratd clinical trial network approach to stroke more broadly and cohesively as a Regional Coordinating Center (RCC) of the NSTN. Our goals are to (1) efficiently implement trials, recruit and retain participants, and optimize data quality as an RCC, (2) actively participate in the NSTN as experienced scientists, clinicians, trialists, and coordinators, and (3) successfully train the next generation of stroke clinical trialists. We will achieve these goals by bringing experienced leadership, access to a diverse patient population, an established research infrastructure, and a supportive administration. Our institution has shown their commitment to the NSTN by agreeing to use a standardized Master Trial Agreement, employ a centralized IRB review, and provide additional institutional funds to support the RCC trainee. We propose to be a key partner in the NSTN working to bring the most clinically impactful stroke therapies to our patients through high-quality stroke trials.