Clinical and Translational Pilot Grant Program

临床和转化试点资助（CTPG） KCA的总体目标是在西方IDeA州的研究人员中建立临床和转化研究能力和校外资助成功。针对西部地区IDeA州独特的区域健康问题的临床和转化研究主要在理学院、文科和相关健康科学学院、公共卫生、护理、社会工作、心理学和相关专业的部门进行。然而，这些项目和计划往往资金不足，与不充分的基础设施支持作斗争，受到有限的教师释放时间的限制，彼此隔离，范围有限。综合试点项目方案的支持将大大加快这些现有努力，使其达到与独立校外资金竞争的水平。在过去的十年里，美国国立卫生研究院资助的西部地区IDeA州的研究出现了前所未有的增长，这主要归功于COBRE和INBRE项目的支持。总的来说，这些COBRE和INBRE项目非常成功，但它们几乎完全集中在临床前研究上。很少有支持或基础设施可以帮助这些有才华的临床前研究骨干进入转化研究。该KCA将实施一项计划，以资助试点拨款，支持可能导致美国国立卫生研究院独立资助临床和转化研究人员的项目。奖励将基于对科学价值的审查以及拟议的研究与CTN-IN的使命的一致性。我们将征求临床和转化研究项目的建议，主题包括但不限于西部地区IDeA各州农村和弱势群体的健康问题和医疗保健机会。投入该项目的资金将转化为高收益的投资回报，因为研究人员将开展跨学科合作，并产生主要数据证明，以加速成功的校外资助，最终加速医疗保健提供者采用变革性的健康相关发现。

Overview and Specific Aims The overall objective of the Clinical and Translational Pilot Grant (CTPG) KCA is to build clinical and translational research capacity and extramural funding success among researchers in the Western IDeA states. Clinical and Translational Research addressing the unique regional health issues of the Western Region IDeA states has been carried out mainly in colleges of science, liberal arts, and allied health sciences, in departments of public health, nursing, social work, psychology, and related programs. However, these projects and programs are often underfunded, struggling with inadequate infrastructure support, constrained by limited availability of faculty release time, isolated from one another, and limited in scope. Support from a comprehensive pilot project program will substantially accelerate these existing efforts and bring them to a level competitive for independent extramural funding. The last decade has seen an unprecedented increase in NIH-funded research within the Western Region IDeA states, largely due to the support from COBRE and INBRE programs. Overall, these COBRE and INBRE programs have been very successful, but they have been focused almost entirely on pre-clinical research. There has been little support or infrastructure available to help this talented cadre of pre-clinical investigators move into translational research. This KCA will implement a program to fund pilot grants supporting projects likely to lead to independent NIH funding for both clinical, and translational, investigators. Awards will be based on reviews of scientific merit and the alignment of the proposed research with the mission of the CTN-IN. We will solicit proposals for clinical and translational research projects on topics including, but not limited to, health issues and health care access among rural and vulnerable populations in the Western Region IDeA states. The funds devoted to this program will translate to a high yield return on investment as investigators develop interdisciplinary collaborations and generate proof of principal data to accelerate successful extramural grant funding, ultimately hastening the adoption of transformative health-related discoveries by health care providers.