Chemistry Biology Interface Training Program

 描述(由申请人提供)：这是加州大学洛杉矶分校化学-生物学接口(CBI)博士前培训项目的第四次续签申请，该项目自1993年以来一直受到资助。加州大学洛杉矶分校CBI培训计划的目标是培养在未来几十年领导化学和生物学之间的研究和培训的科学家。加州大学洛杉矶分校需要CBI项目的理由是，尽管有跨学科的互动和合作，但博士培训在每个系往往是传统的和孤立的，强调狭窄专业的课程和培训。尽管一门学科内的深度培训是必要和重要的，但下一代科学家也将需要 接受跨学科的教育，以便在这个现代社会发挥最大的效力。加州大学洛杉矶分校的CBI项目打破了部门之间的隔离，让学员沉浸在跨越化学和生物界面的最先进的跨学科研究中，从而提供了这一点。参加培训的学员来自化学和生物化学系的所有研究领域，以及分子和医学药理学、微生物学、免疫学和分子遗传学、分子、细胞和发育生物学、化学工程和生物工程系，以及分子生物学研究所、神经科学计划和ACCESS计划。研究生实习生所从事的研究是：(1)具有强大的有机、物理或分析化学成分，(2)解决化学/生物学界面上尚未解决的重大问题。该计划的主要要求是(1)完成化学205A课程，这是一门跨学科的研究生水平课程，题为“生物化学入门”，化学205B，“化学-生物学接口问题”，这门课程旨在为学员提供有关可在他们的研究中实施的技术的信息，以及化学203B，伦理培训。(2)学生还将参加化学206，这是一个每周一次的午餐研讨会课程，包括在化学生物学界面对尖端研究的深入审查和讨论，以及实习生报告，以及(3)参加跨学科的研究实习。培训计划为期三年，12名博士前实习生被要求满足这一培训计划的一些强烈需求。该计划将生物学方面的业余天才化学家转变为能够识别和解决生物学中最重要的问题并与生物学家高度合作的化学家。它还将使用化学技术作为黑匣子的生物学家变成了一名专家，他为研究生物学的化学方法的发展做出了贡献，可以找到解决他们生物问题的新的化学方法，并且愿意与化学家合作。这一连贯和互动的培训计划也大大加强了加州大学洛杉矶分校的科学和教育环境。

 DESCRIPTION (provided by applicant): This is the application for the fourth renewal of the UCLA Chemistry-Biology Interface (CBI) Predoctoral Training Program, which has been funded since 1993. The objective of the UCLA CBI Training Program is to educate the scientists who will lead research and training at the interface between chemistry and biology in the decades to come. The rational for needing a CBI program at UCLA is that despite interactions and collaborations across disciplines, Ph.D. training is often traditional and insular in each department, emphasizing courses and training in a narrow specialty. Although deep training within a discipline is necessary and important, the next generation of scientists will also need to be educated across disciplines to be maximally effective in this modern era. The UCLA CBI Program provides this by breaking down the isolation between departments, and immersing trainees in state-of-the-art interdisciplinary research that spans the interface of chemistry and biology. Participating trainees come from all research areas of the Department of Chemistry and Biochemistry, as well as from the Departments of Molecular & Medical Pharmacology, Microbiology, Immunology & Molecular Genetics, Molecular, Cell & Developmental Biology, Chemical Engineering, and Bioengineering, and from the Molecular Biology Institute, Neuroscience Program, and Access Program. Graduate student trainees are involved in research that (1) has a strong organic, physical, or analytical chemistry component and (2) addresses significant unsolved problems at the Chemistry/Biology interface. The major requirements of the program are (1) completion of Chem205A, an interdisciplinary graduate level course entitled "Introduction to Chemistry of Biology," Chem205B, "Issues on the Chemistry-Biology Interface" a course designed to provide trainees with information about techniques that can be implemented in their research, and Chem203B, ethics training. (2) Students will also participate in Chem206, a weekly luncheon seminar course consisting of intensive review and discussion of cutting- edge research at the chemistry biology interface and trainee presentations, and (3) participation in a cross-disciplinary research internship. The training program is for three years and twelve predoctoral trainees are requested to meet some of the strong demand for this training program. The program converts brilliant chemists who are amateurs in biology into chemists who can identify and solve the most important problems in biology and who are highly collaborative with biologists. It also turns the biologist using a chemical technique as a black box into an expert who contributes to the development of chemical methods to study biology, can identify new chemical approaches to solve their biological problems, and who are comfortable collaborating with chemists. This coherent and interactive training program also has significantly strengthened the scientific and educational environment at UCLA.