Meta-Regression to Identify the Impact of SBIRT Structure and Content on Outcome

描述（由申请人提供）：这是对PAR-14-052“酒精使用障碍治疗中的行为改变机制”（R03）的回应，题为“Meta-Regression以确定SBIRT结构和内容对结果的影响”。在初级保健中筛查、短暂干预和转诊治疗高危酒精使用已显示出很强的疗效，并被推荐作为常规临床护理的一部分。尽管如此，只有不到16%的美国人报告被医疗保健提供者询问过酒精使用情况。关于SBIRT中行为改变的机制知之甚少，这些信息有望提高培训和实施工作的有效性。meta分析中纳入的SBIRT研究结果存在显著的无法解释的异质性。研究报告包括关于SBIRT协议的结构和内容的有限细节。该项目的目的是开发一种工具来测量科学报告中未描述的SBIRT协议的特征，并使用元回归来确定其对结果的影响。研究样本将包括来自2012年乔纳斯初级保健中SBI荟萃分析的23项对照试验。此外，还将创建一个网站，作为协议描述和材料的存储库。拟议的项目旨在利用以往研究投资的创新方法，确定SBIRT背后的行为改变机制。

DESCRIPTION (provided by applicant): This is a submission in response to PAR-14-052, Mechanisms of Behavior Change in the Treatment of Alcohol Use Disorders (R03), titled Meta-Regression to Identify the Impact of SBIRT Structure and Content on Outcome. Screening, brief intervention, and referral to treatment for risky alcohol use in primary care has shown strong efficacy and is recommended as part of routine clinical care. Despite this, fewer than 16% of Americans report having been asked about alcohol use by a healthcare provider. Little is known about the mechanism of behavior change in SBIRT and such information holds promise to improve the effectiveness of training and implementation efforts. There is significant unexplained heterogeneity in the results of SBIRT studies included in meta-analysis. Research reported includes limited details about the structure and content of SBIRT protocols. The purpose of this project is to develop an instrument to measure characteristics of SBIRT protocols that are not described in scientific reports and use meta-regression to determine their impact on outcome. The study sample will include 23 controlled trials from the 2012 Jonas meta-analyses on SBI in primary care. In addition, a website will be created that will serve as a repository for protocol descriptions and materials. The proposed project seeks to identify the mechanisms of behavior change underlying SBIRT using an innovative methodology that takes advantage of previous research investments.