Pelvic Floor Disorders Network Clinical Sites

描述（由申请人提供）：骨盆底疾病是常见的，令人烦恼的，治疗不充分。来自拟议中的犹他州大学骨盆底疾病网络临床站点的研究人员的首要目标是改善女性在骨盆底功能障碍领域的健康。为此，具体目标包括：1）确定研究的优先领域，2）开发评估工具，3）开发和实施PFDN方案4）招募和招募PFDN方案中的受试者，5）实现目标招募目标和高受试者保留率6）确保高质量数据7）将数据准确传输到数据协调中心，8）参与数据分析，9）向研究界传播结果，以及10）产生高质量的出版物本提案中概述的随机临床试验的广泛科学目的是评估与常规护理相比，阴道手术后立即放置子宫托是否能改善盆腔器官脱垂的解剖成功。 相关性：四分之一的美国女性有中度至重度的骨盆底疾病症状。改善这些疾病的预防、诊断和治疗至关重要。犹他州大学为我们在这一领域的知识做出了重大贡献，并证明了它有能力充分参与骨盆底疾病网络的合作机制。通过继续参与这一网络，犹他州研究中心的多学科研究小组计划进一步促进妇女的医疗保健。

DESCRIPTION (provided by applicant): Pelvic floor disorders are common, bothersome, and inadequately treated. The overarching aim of the investigators from the proposed University of Utah Pelvic Floor Disorders Network Clinical Site is to improve women's health in the area of pelvic floor dysfunction. To this end, site specific aims include: 1) Identifying priority areas of research, 2) Developing assessment tools, 3) Developing and implementing PFDN protocols 4) Recruiting and enrolling subjects in PFDN protocols, 5) Achieving on-target recruitment goals and high subject retention 6) Ensuring high-quality data 7) Transmitting data accurately to the Data Coordinating Center, 8) Participating in data analysis, 9) Disseminating results to the research community, and 10) Producing high-quality publications The broad scientific aim for the randomized clinical trial outlined in this proposal is to evaluate whether a pessary placed immediately after vaginal surgery for pelvic organ prolapse improves anatomic success compared to usual care. RELEVANCE: One in four American women has moderate to severe symptoms of pelvic floor disorders. Improving prevention, diagnosis and treatment of these disorders is crucial. The University of Utah has contributed substantially to our knowledge in this area and has demonstrated its ability to fully participate in the cooperative mechanism of the Pelvic Floor Disorders Network. Through continued participation in this network, the multi-disciplinary team of Utah site investigators plan to progress women's healthcare further.