IGF::OT::IGF STABILITY STUDY OF METHOTREXATE AND PLACEBO CAPSULES
IGF::OT::IGF STABILITY STUDY OF METHOTREXATE AND PLACEBO CAPSULES
批准号:
9149464
负责人:
Jon Carl Mirsalis
金额:
$9.58万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2015
资助国家:
美国
项目状态:
已结题
起止时间:
2015-08-01 至 2018-11-30
关键词:
Acquired Immunodeficiency SyndromeBiological AssayContractsDevelopmentDevelopment PlansDrug Delivery SystemsDrug FormulationsExcipientsGoalsHIV InfectionsImmune responseIn VitroMasksMethotrexateNational Institute of Allergy and Infectious DiseasePermeabilityPharmaceutical PreparationsPharmacologic SubstancePlacebosPowder dose formPropertyResearch PersonnelServicesSolubilityTabletsTaste PerceptionTherapeutic AgentsUnited States Dept. of Health and Human ServicesUnited States National Institutes of Healthabsorptioncapsuleclinical investigationco-infectiondosagedrug developmentmicrobicidepreventprogramssexual HIV transmission
中文摘要
国家过敏和传染病研究所(NIAID)、国家卫生研究院(NIH)、卫生与公众服务部(DHHS)获得性免疫缺陷综合症(DAIDS)司维持着一系列合同,以支持开发(1)艾滋病毒感染及其并发症和合并感染的疗法,以及(2)预防艾滋病毒性传播的杀菌剂。根据该合同提供的服务帮助学术机构的研究人员和小型制药公司在他们将其产品推向临床研究时填补其药物开发计划中的具体空白。该计划的目标是进行研究,以支持潜在治疗剂和杀微生物剂配方的开发。靶向制剂应包括片剂、胶囊、冻干粉。
英文摘要
The Division of Acquired Immunodeficiency Syndromes (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), maintains a portfolio of contracts to support the development of (1) therapies for HIV infection and its complications and coinfections, and (2) microbicides for preventing the sexual transmission of HIV. Services provided under this contracts assist investigators in academic settings and small pharmaceutical firms in filling specific gaps in their drug development plan as they advance their product towards clinical investigation. The goal of the program is to conduct studies to support the development of formulations of potential therapeutic agents and microbicides. Targeted formulations shall include tablets, capsules, lyophilized powders.,
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Task Order 3: Interventional Agent Development Services Program
-
批准号:10704968
-
项目类别:
-
资助金额:$1.17万
-
财政年份:2018
-
负责人:Jon Carl Mirsalis
-
依托单位:
Task Order 3:Interventional Agent Development Services Program
-
批准号:9452777
-
项目类别:
-
资助金额:$47.24万
-
财政年份:2017
-
负责人:Jon Carl Mirsalis
-
依托单位:
Task Order 5: The Interventional Agent Development Services Program
-
批准号:9616145
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项目类别:
-
资助金额:$8.95万
-
财政年份:2017
-
负责人:Jon Carl Mirsalis
-
依托单位:
Task 4: The Interventional Agent Development Services program
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批准号:9430224
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项目类别:
-
资助金额:$191.89万
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财政年份:2017
-
负责人:Jon Carl Mirsalis
-
依托单位:
Task Order 3: Interventional Agent Development Services Program
-
批准号:9452779
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项目类别:
-
资助金额:$6.19万
-
财政年份:2017
-
负责人:Jon Carl Mirsalis
-
依托单位:
Task Order 5: The Interventional Agent Development Services Program
-
批准号:9475640
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项目类别:
-
资助金额:$8.72万
-
财政年份:2017
-
负责人:Jon Carl Mirsalis
-
依托单位:
Task Order 5: The Interventional Agent Development Services Program
-
批准号:9475639
-
项目类别:
-
资助金额:$8.72万
-
财政年份:2017
-
负责人:Jon Carl Mirsalis
-
依托单位:
Task Order 5: The Interventional Agent Development Services Program
-
批准号:9475638
-
项目类别:
-
资助金额:$8.72万
-
财政年份:2017
-
负责人:Jon Carl Mirsalis
-
依托单位:
Task 4: The Interventional Agent Development Services program
-
批准号:9430227
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项目类别:
-
资助金额:$42.74万
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财政年份:2017
-
负责人:Jon Carl Mirsalis
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依托单位:
Task 6: Technical Support for Tuberculosis Therapeutics
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批准号:9533345
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项目类别:
-
资助金额:$68.37万
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财政年份:2017
-
负责人:Jon Carl Mirsalis
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依托单位:
Task Order 2: The Interventional Agent Development Services Program
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批准号:9430046
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项目类别:
-
资助金额:$10.98万
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财政年份:2016
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负责人:Jon Carl Mirsalis
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依托单位:
Task Order 2: The Interventional Agent Development Services Program
-
批准号:9430043
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项目类别:
-
资助金额:$19.8万
-
财政年份:2016
-
负责人:Jon Carl Mirsalis
-
依托单位:
Task Order 2: The Interventional Agent Development Services Program
-
批准号:9430040
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项目类别:
-
资助金额:$25.43万
-
财政年份:2016
-
负责人:Jon Carl Mirsalis
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依托单位:
IGF::OT::IGF PHARMACOLGY AND TOXICOLOGY STUDIES OF AMAKACIN AND SUTEZOLID, AND SUPPORT THE DEVELOPMENT OF BIOMARKER AND MITOCHONDRIAL TOXICITY ASSAYS
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批准号:9337303
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项目类别:
-
资助金额:$3.65万
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财政年份:2014
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负责人:Jon Carl Mirsalis
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依托单位:
IGF::OT::IGF PHARMACOLGY AND TOXICOLOGY STUDIES OF AMAKACIN AND SUTEZOLID, AND SUPPORT THE DEVELOPMENT OF BIOMARKER AND MITOCHONDRIAL TOXICITY ASSAYS
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批准号:8938944
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项目类别:
-
资助金额:$189.89万
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财政年份:2014
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负责人:Jon Carl Mirsalis
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依托单位:
Task 6: Technical Support for Tuberculosis Therapeutics
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批准号:10704964
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项目类别:
-
资助金额:$6.27万
-
财政年份:2014
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负责人:Jon Carl Mirsalis
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依托单位:
NIAID Preclinical Development Support - HIV-1 Envelope Protein Production
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批准号:8752944
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项目类别:
-
资助金额:$514.02万
-
财政年份:2013
-
负责人:Jon Carl Mirsalis
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依托单位:
IGF::OT::IGF NIAID Preclinical Development Support - cGMP Compliance Audit # 2
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批准号:8752932
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项目类别:
-
资助金额:$19.22万
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财政年份:2013
-
负责人:Jon Carl Mirsalis
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依托单位:
NIAID Preclinical Development Support - Manufacture of HIV-gp120 Proteins
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批准号:8752940
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项目类别:
-
资助金额:$955.5万
-
财政年份:2013
-
负责人:Jon Carl Mirsalis
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依托单位:
Other Functions - NIAID Preclinical Development Support - cGMP Compliance Audit #
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批准号:8752896
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项目类别:
-
资助金额:$7.08万
-
财政年份:2013
-
负责人:Jon Carl Mirsalis
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依托单位:
海外基金