Exergame Physical Activity, Pain, and Functional Mobility Among Women with Knee Osteoarthritis

描述（由申请人提供）：此应用程序要求NCMHD K22差异研究和教育推进使命（梦想）职业过渡奖博士布里奇特拉希姆威廉姆斯，博士，公共卫生硕士。Rahim-Williams博士的目标是开发一个独立的研究项目，研究非裔美国人和非西班牙裔白色女性45-75岁膝关节骨关节炎（OA）中慢性疾病自我管理的少数民族健康和健康差异。Rahim-Williams博士目前正在从事探索性研究，在50-70岁患有膝关节OA的非裔美国人和非西班牙裔白色女性中检查疼痛、运动体力活动和功能活动。通过NIH经验、直接指导、独立研究、科学会议和教学经验，Rahim-Williams博士的职业发展计划将为她提供以下方面的扩展技能、知识和经验：（1）流行病学、先进的生物统计学调查设计、方法和基于人群的数据分析以及导致膝关节OA健康差异的生物心理社会因素;（2）骨关节炎的临床研究，包括评估疾病严重程度，以及膝关节骨关节炎的中枢和外周疼痛机制，（3）设计和实施随机临床试验，以及（4）体力活动和运动游戏技术的技能和知识;健康游戏干预用于改善健康结果。研究计划的主要目的是使用实验室方法描述膝关节OA女性患者的身体活动、疼痛、功能活动和残疾特征，包括：（1）新颖和创新的健康游戏（例如，exergame骑自行车、DanceTown/Dance、Dance Revolution）方法，（2）机械压力测试和（3）评估身体活动、功能活动和自我报告的残疾。该研究项目的目标是增加身体活动，改善功能性活动，并减少受膝关节OA影响的女性的疼痛和残疾结果。K22梦想奖将促进拉希姆-威廉姆斯博士从少数民族健康和健康差距研究人员的早期阶段过渡到独立阶段，利用新颖的健康游戏进行少数民族妇女疼痛和慢性病的自我管理。

DESCRIPTION (provided by applicant): This application requests a NCMHD K22 Disparities Research and Education Advancing Mission (DREAM) Career Transition Award for Dr. Bridgett Rahim-Williams, PhD, MPH. Dr. Rahim-Williams' goal is to develop an independent program of research studying minority health and health disparities in chronic disease self-management among African American, and non-Hispanic white women ages 45-75 with knee osteoarthritis (OA). Dr. Rahim-Williams is currently engaged in exploratory research that examines pain, exergame physical activity and functional mobility among African American and non-Hispanic White women ages 50-70 with knee OA. Through NIH experience, direct mentoring, independent study, scientific meetings, and didactic experiences, Dr. Rahim-Williams' career development plan will provide her with expanded skills, knowledge and experience in: (1) epidemiological, advanced bio- statistics survey design, methods, and analysis of population-based data and biopsychosocial factors contributing to health disparities in knee OA; (2) clinical research in osteoarthritis, including assessment of disease severity, and central and peripheral pain mechanisms in knee osteoarthritis, (3) design and conduct of randomized clinical trials, and (4) skills and knowledge in physical activity and exergaming technology; Games for Health intervention applied to improve health outcomes. The main objectives of the research plan are to characterize physical activity, pain, functional mobility and disability among women with knee OA using experimental laboratory methods that include: (1) novel and innovative Games for Health (e.g. exergame cycling, DanceTown/Dance, Dance Revolution) methods, (2) mechanical pressure testing and (3) assessment of physical activity, functional mobility and self-reported disability. The goal of this research project is to increase physical activity, improve functional mobility, and reduce pain and disability outcomes for women affected by knee OA. The K22 DREAM award will facilitate Dr. Rahim-Williams' transition from the early stage as a minority health and health disparities researcher to the independent stage of investigator-initiated health disparities research utilizing novel games for health for self-management of pain and chronic disease among minority women.