Center for Environmental Health Sciences

描述（由申请人提供）：本申请请求继续为环境健康科学中心（CEHS）提供COBRE支持，该中心成立于2000年，目标是发展一个具有全国竞争力的跨学科研究项目，研究人类疾病的机制和环境对这些疾病的影响。COBRE I和II奖（分别为2002年和2007年）通过CEHS的支持加强了该机构的生物医学研究基础设施，并提高了研究人员独立竞争外部同行评议支持的能力。聘请和指导教师，建立设施核心，并支持研究项目，导致外部资助资金和CEHS研究人员的出版物大幅增长。蒙大拿大学在财政支持和大量新的研究空间方面为成功做出了重大贡献。建立了一个战略计划，通过以下目标将CEHS转变为一个可持续的长期中心：目标1：鼓励和促进合作研究，以实现研究项目和核心的可持续性。这一目标将通过战略计划来实现，即继续培养CEHS研究人员，通过强有力的建议和高效互动的设施核心来预测和瞄准研究机会。目标2：利用试点资助计划、培训机会和外部专业知识，以CEHS资助的研究组合为基础。试点项目计划将用于资助最有前途的研究，培训机会将在竞争的基础上提供，以支持研究人员继续教育的机会，外部专家（外部咨询委员会和邀请专家）将提供科学指导。目标3：提供领导和行政支持，并继续评估和完善中心和核心业务。领导和行政支持将提供关键的基础设施，以促进研究者的研究成功，评估将用于确定有效性。目标4：利用蒙大拿大学的承诺，利用COBRE的支持来实现中心长期可持续性的目标。

DESCRIPTION (provided by applicant): This application requests continuance of COBRE support for the Center for Environmental Health Science (CEHS) which was established in 2000 with the goal of developing a nationally competitive interdisciplinary research program to study the mechanisms of human disease and environmental impacts on those diseases. The COBRE I and II awards (2002 and 2007, respectively) strengthened the institution's biomedical research infrastructure through the support of the CEHS and enhanced the ability of investigators to compete independently for external peer-reviewed support. Faculty were hired and mentored, Facility Cores were established, and research projects were supported resulting in substantial growth of external grant funding and publications from CEHS investigators. The University of Montana contributed significantly to the success with financial support and substantial new research space. A strategic plan has been established to transition CEHS into a sustained long-term center through the following aims: Aim 1: Encourage and facilitate collaborative research to achieve sustainability of the research program and cores. This Aim will be accomplished through the Strategic Plan to continue to develop CEHS investigators, anticipate and target research opportunities with strong proposals and a highly effective and interactive Facility Cores. Aim 2: Utilize the pilot grant program, training opportunities and external expertise to build on the CEHS funded research portfolio. The pilot project program will be used to fund the most promising research, training opportunities will be provided on a competitive basis to support continued education opportunities to investigators, and external expertise (External Advisory Committee and invited experts) will provide scientific guidance. Aim 3: Provide leadership and administrative support and continue to evaluate and refine center and core operations. Leadership and administrative support will provide critical infrastructure to facilitat investigator's research success and evaluation will be used to determine effectiveness. Aim 4: Utilize the University of Montana commitment to leverage the COBRE support to achieve the goal of long-term center sustainability.