Systems Biology Bioinformatics Core

项目摘要/摘要 生物信息学是为该中心提出的整个系统生物学计划的关键要素 转化性儿科研究(CTPR)，是由 科布雷项目的领导者。系统生物学生物信息学核心将成为新的核心，以满足 拟建的科布雷中心的研究需求。将组建一个由五名生物信息学家组成的团队， CTPR所涵盖的所有研究领域的广泛专业知识。系统生物学生物信息学核心将 与CTPR蛋白质组学和基因组学核心密切合作，提供独一无二的系统生物学 儿科疾病研究的方法。这种协调的核心结构将使生物信息学能够 集成到跨学科框架中，能够支持所有技术和 临床和基础研究采用有效的系统生物学方法所需的专业知识。亲密互动 系统生物学生物信息学核心和科布雷中心项目负责人之间的合作也将带来新的 研究方面的创新将使未来的Cobre研究人员以及更广泛的校园研究受益 社区。核心主任将提供系统生物学、生物信息学方面的机会和培训 致CTPR成员、校园和阿肯色州的研究人员。

PROJECT SUMMARY/ABSTRACT Bioinformatics is a key element of the overall systems biology program proposed for the Center for Translational Pediatric Research (CTPR) and is an essential component of the Research Projects proposed by the COBRE Project Leaders. The Systems Biology Bioinformatics Core will be a new core created to meet the research needs of the proposed COBRE Center. A team of five bioinformaticians will be assembled that have broad expertise in all research areas covered by the CTPR. The Systems Biology Bioinformatics Core will coordinate closely with the CTPR Proteomics and Genomics Cores to provide a one-of-a-kind systems biology approach for pediatric disease research. This coordinated core structure will allow bioinformatics to be integrated into a cross-disciplinary framework capable of supporting the entire range of technologies and expertise needed for an effective systems biology approach for clinical and basic research. Close interaction between the Systems Biology Bioinformatics Core and COBRE Center Project Leaders will also lead to new innovations in research that will benefit future COBRE investigators as well as the broader campus research community. Opportunities and training in systems biology bioinformatics will be provided by the Core Directors to CTPR members, the campus and researchers in Arkansas.