Genomics and Molecular Biology

项目概要/摘要：基因组学与分子生物学共享资源 基因组学和分子生物学共享资源（GMBSR）于2013年创建， 基因组学与分子生物学共享资源。合并加强了 核心之间的沟通，最大限度地利用工作人员的专业知识，并提高质量， 为研究人员提供服务。GMBSR提供下一代测序（Ion Torrent和Illumina）， 桑格测序除了微阵列服务（Illumina和Affyssin），NanoString技术，和 共享仪器，包括qPCR热循环仪。强制性免费咨询有关实验 设计和预算估计数提供给每一个发起新项目的研究人员。GMBSR直接 由克雷格汤姆林森博士，基因组学位于黎巴嫩在诺里斯棉花癌症中心（NCCC）， 而分子生物学则以汉诺威校区为基础。基因组学，由联合主任乔安娜监督 汉密尔顿，博士，包括一个经验丰富的技术人员和生物信息学家。分子生物学由Co- 主任约兰达桑切斯博士，博士，并配备了一名高级技术员/经理和技术专家。 GMBSR是最广泛使用的NCCC共享资源，支持超过170个生物医学实验室， 达特茅斯研究团体，其中大约一半是由NCCC领导的实验室 六个NCCC研究项目中的五个（癌症流行病学，癌症机制， 分子治疗学、癌症成像与放射生物学、免疫学与癌症免疫治疗）。的 快速变化的基因组学领域对GMBSR提出了独特的挑战。为了满足需要， 通知NCCC研究者，GMBSR举办研讨会，出席实验室会议和肿瘤委员会; 在当地研讨会上发言，并参加国家和地区技术会议，以了解最新情况 技术、技巧和方法。

Project Summary/Abstract: Genomics & Molecular Biology Shared Resource The Genomics & Molecular Biology Shared Resource (GMBSR) was created in 2013 by combining the Genomics Shared Resource with the Molecular Biology Shared Resource. The merger enhanced the communication between the cores, maximized the utilization of staff expertise, and raised the quality of services offered to researchers. The GMBSR offers next generation sequencing (Ion Torrent and Illumina) and Sanger sequencing in addition to microarray services (Illumina and Affymetrix), NanoString technology, and shared instrumentation, including qPCR thermocyclers. Mandatory free consultation regarding experimental design and budget estimates are provided to every researcher initiating a new project. The GMBSR is directed by Craig Tomlinson, PhD, with Genomics located in Lebanon at the Norris Cotton Cancer Center (NCCC), while Molecular Biology is based on the Hanover campus. Genomics, overseen by Co-Director Joanna Hamilton, PhD, includes an experienced technician and a bioinformaticist. Molecular Biology is led by Co- Director Dr. Yolanda Sanchez, PhD, and is staffed by a Senior Technician/Manager and a technical specialist. The GMBSR is the most widely used NCCC Shared Resource, supporting over 170 biomedical laboratories in the Dartmouth research community, of which approximately one-half are laboratories led by NCCC investigators in five of the six NCCC Research Programs (Cancer Epidemiology, Cancer Mechanisms, Molecular Therapeutics, Cancer Imaging & Radiobiology, and Immunology & Cancer Immunotherapy). The rapidly changing field of Genomics presents unique challenges to the GMBSR. To meet the needs of and to inform NCCC investigators, the GMBSR conduct workshops, present at laboratory meetings and tumor boards; speak at local seminars, and attend national and regional technology conferences to learn the latest technologies, techniques, and methods.