Biocatalyst Platform Technology for Enhancing Cometabolic Biodegradation

项目摘要/摘要 美国水资源受到有害有机化合物的污染继续构成 公共卫生和安全面临严重而普遍的风险。有害有机化合物包括氯化溶剂， 碳氢化合物、消毒副产品、杀虫剂、多环芳烃(PAHs)、多氯联苯(PCbs)、 以及其他外来的(非自然产生的)有机化学品。因为这些化合物构成了275个化合物中的大部分 有毒物质和疾病登记局(ATSDR)将危险物质列为高度优先的危险物质 美国环境保护署(US EPA)和州监管机构设定了雄心勃勃的治疗方案 这些危险物质的目标通常是致癌物质。除了增加患癌症的风险外，非常小的 大量的有害有机化合物已被证实会导致多种疾病，包括肝脏或肾脏。 疾病、免疫功能障碍、神经系统紊乱以及荷尔蒙或生殖缺陷。 有害有机化合物的修复是困难和昂贵的。超级基金网站经理、市政当局和 全国各地的自来水供应商都在要求更便宜、更有效的有害物质处理方案 有机化合物比现有的一套能源密集型和产生废物的传统技术更具优势。具体来说， 需要新的技术来将多种有害有机化合物的处理整合为简单、 环境友好、易于使用的系统，具有尽可能少的工艺单元。 这项提议试图通过一种新的增强共代谢技术来满足这一需求。与传统的 物理或化学技术，如空气剥离和活性碳，这项新技术降低了有害物质 将有机化合物转化为无害的副产品，而不是产生集中的二次废物流。此外，这一点 与化学或紫外线氧化相比，新技术显著降低了能源和维护成本。 作为一种原位和非原位治疗选项，这项新技术设计灵活，可在 一系列动态操作条件，可同时降解数百种有害有机化合物。 在这个第二阶段的项目中，设计、建造、优化和测试了一个处理危险有机物质的放大中试工厂。 在一个备受瞩目的受污染地点发现了化合物。该项目为新的 技术，同时让试点工厂进行一系列黄金标准的压力测试，以获得关键的运营边界。 最终，该项目建立了实施所需的详细设计标准和技术经济分析 这项新技术解决了超级基金网站的各种紧急需求，市政饮用水， 分散处理、废水再利用和再循环以及农业和工业水处理部门。 该项目的成果是开发了首个用于降解复杂组合的技术 水中的有害有机化合物。该项目的成功成果在解决以下问题方面具有重大希望 使用现有技术无法有效处理的有害污染物，从而确保了实质性的价值 为子孙后代提供公共和私人环境管理。

Project Summary / Abstract The contamination of the water resources in the United States with hazardous organic compounds continues to pose serious and widespread risks to public health and safety. Hazardous organic compounds include chlorinated solvents, hydrocarbons, disinfection byproducts, pesticides, polyaromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and other xenobiotic (not naturally occurring) organic chemicals. As these compounds comprise a majority of the 275 “high-priority” hazardous substances ranked by the Agency of Toxic Substances and Disease Registry (ATSDR), the United States Environmental Protection Agency (US EPA) and state regulatory agencies have set ambitious treatment goals for these dangerous and often carcinogenic substances. In addition to increased risks for cancer, very small concentrations of hazardous organic compounds have been proven to cause various illnesses including liver or kidney disease, immune dysfunction, nervous system disorders, and hormonal or reproductive defects. The remediation of hazardous organic compounds is difficult and costly. Superfund site managers, municipalities and water suppliers across the country are demanding less expensive and more effective treatment options for hazardous organic compounds than the existing suite of energy-intense and waste-producing conventional technologies. Specifically, there is a need for new technologies to consolidate the treatment of multiple hazardous organic compounds into simple, environmentally friendly, and easy-to-use systems with as minimal process units as possible. This proposal seeks to address this need through a novel enhanced cometabolism technology. In contrast to conventional physical or chemical technologies such as air stripping and activated carbon, this new technology degrades the hazardous organic compounds into harmless byproducts instead of producing a concentrated secondary waste stream. Moreover, this new technology offers significant reductions in energy and maintenance costs compared with chemical or UV oxidation. Flexibly designed as both an in-situ and ex-situ treatment option, this new technology offers reliable performance across a range of dynamic operating conditions to achieve simultaneous degradation of hundreds of hazardous organic compounds. In this Phase II project, a scaled-up pilot plant is designed, constructed, optimized, and tested to treat hazardous organic compounds at a high-profile contaminated site. This project establishes the long-term performance profile for the new technology while engaging the pilot plant in a series of gold-standard stress tests to obtain key operational boundaries. Ultimately, the project establishes the detailed design criteria and technoeconomic analysis necessary for implementing this new technology to address a variety of urgent needs across the Superfund site, municipal drinking water, decentralized treatment, wastewater reuse and recycle, and agricultural and industrial water treatment sectors. The outcome of this project is the development of a first-of-its-kind technology for degrading complex combinations of hazardous organic compounds in water. The successful result of this project holds significant promise in addressing harmful contaminants that are not effectively treatable using existing technologies, and thereby securing substantial value for public and private environmental stewardship for future generations.