Administrative Core

项目总结 肯塔基大学(英国)癌症和代谢中心(CCM)将作为一个独特的 多学科生物医学研究卓越中心(COBRE)旨在开发和部署 经过战略设计的可持续中心基础设施，培养专注于 代谢失调在癌症发生发展中的作用。管理核心提供 关键的科学和行政领导，以推进CCM的目标：制定和维持 专注于主题的多学科中心基础设施，致力于定义新陈代谢在 癌症的开发和治疗，并利用这一新平台开发有前途的早期 在一个令人兴奋的癌症研究新领域，拥有增强技能的研究人员。行政管理的目标 核心是通过提供高效的管理来提高中心教职员工的科学生产力 通过组织/领导跨科学项目和核心以及试点项目提供服务 该框架支持灵活的基于团队的指导，并提供明确的责任。因此，CCM 行政核心是负责整合高度互补性的中央协调中心 英国在癌症、新陈代谢和数据科学方面的学科优势，并利用先进的 代谢组学工具和先进的癌症成像能力。核心对实现 CCM的科学愿景，以基于变革性领导和共享的原则运作 行政监督。行政核心职能将通过以下三个方面运作 具体目标：1)提供中心的协调运行管理；2)促进和协调 研究培训、指导和职业发展活动，以培养癌症早期研究人员 和代谢，并通过试点扩大这一领域的研究；以及3)协调和开展 统筹谋划和评估。该核心将协调和执行本组织的所有行政活动 CCM：监督中心的日常活动；协调项目沟通、财务流程、会议 组织和咨询委员会的投入；促进和加快项目和核心之间的互动； 管理试点项目计划；领导计划和项目评估工作。该核心将监督一个 目前共有四个项目、两个核心和一个生物统计和生物信息学支助部分，并确保 高效、规划良好的基于团队的指导，包括基本和临床观点以及外部 专业知识，适用于所有早期调查人员。

PROJECT SUMMARY The University of Kentucky (UK) Center for Cancer and Metabolism (CCM) will be established as a unique multidisciplinary Center of Biomedical Research Excellence (COBRE) designed to develop and deploy a strategically designed, sustainable center infrastructure that cultivates cutting-edge research focused on the role of metabolic dysregulation in cancer development and progression. The Administrative Core provides critical scientific and administrative leadership to advance the goals of the CCM: to develop and sustain a thematically focused multidisciplinary center infrastructure dedicated to defining the role of metabolism in the development and treatment of cancer and to use this novel platform to develop promising early-stage investigators with enhanced skills in an exciting new area of cancer research. The goal of the Administrative Core is to enhance the scientific productivity of the center's faculty by delivering efficient administrative services across scientific projects and cores as well as pilot projects through an organizational/leadership framework that supports flexible team-based mentoring and provides for clear accountability. Thus, the CCM Administrative Core is the central coordinating hub responsible for integrating highly complementary disciplinary strengths at UK in cancer, metabolism, and data sciences and leveraging sophisticated metabolomics tools and advanced cancer imaging capabilities. The core has primary responsibility for realizing the CCM's scientific vision, operating on principles grounded in transformational leadership and shared administrative oversight. Administrative Core functions will be operationalized through the following three specific aims: 1) to provide coordinated operational management of the center; 2) to facilitate and coordinate research training, mentoring and career development activities to develop early-stage investigators in cancer and metabolism and expand research in this area through pilot projects; and 3) to coordinate and conduct overall planning and evaluation. The core will coordinate and implement all administrative activities of the CCM: oversee daily center activities; coordinate program communications, fiscal processes, meeting organization, and advisory committee input; facilitate and expedite interactions among projects and cores; manage the pilot project program; and lead program and project evaluation efforts. The core will oversee a total of four current projects, two cores, and a biostatistics and bioinformatics support component and ensure highly effective, well-planned team-based mentorship, including basic and clinical perspectives and external expertise, for all early-stage investigators.