Translational Training in Addiction

描述（由申请人提供）：本提案寻求NIDA T32赠款（DA 022981）的竞争性续期，以支持UAMS培训计划“成瘾转化培训”。“该计划最初于2009年获得资助，旨在提供多层次、跨学科的团队科学培训，涵盖转化成瘾研究的分子到社区组成部分。定量和定性数据支持当前培训计划的出色成果。拟议的计划计划扩展了培训目标，以实现最先进的最佳实践方法，在不断扩大的学术和非学术劳动力以及基础和临床研究学术环境中培训下一代影响成瘾科学家。项目评估基于与七个培训目标相关的进展，包括（1）开发药物使用障碍的科学，临床和社会作用和影响的共享知识，（2）提供成瘾研究职业发展的个性化路径，（3）提供强调跨学科，团队科学，转化研究的学习环境，（4）提供研究伦理和多样性方面的基础和培训，（5）消除独立和培训后安置的障碍，（6）监测受训人员和项目进展，以及（7）培养成瘾医生科学家。计划的行政和管理将通过计划主任、指导委员会和治理委员会的协调互动来完成。需要为四个级别的受训人员提供支助：3名博士预科生、4名博士后和4名医科学生暑期实习生。这将得到一名PGY 3精神病学住院医师的机构支持的补充。全计划和轨道选择性教学法将支持跨学科T0（分子目标识别）-T4（实施科学）转化研究培训机会，在广泛的学术以及政府成瘾研究环境中，强调受训者与受训者和受训者与教师的互动。将定期监测和评估与职业发展里程碑相关的受训人员和计划成功情况。职业发展的障碍将通过该方案的“独立之路”部分加以解决。重要的，多层次的机构承诺和资源支持该计划的价值和持续的成功。一个由受训人员领导的社区外展部分将教育地方和州社区并使其参与解决吸毒成瘾问题。基于3年以上的计划经验，UAMS的NIDA T32培训计划已经完成了其最初的目标，即有效地培训人口统计学上多样化和道德意识的成瘾研究人员，并将受训人员置于竞争激烈的博士后和教师学术职位，以及影响培训医生对成瘾研究的认识和赞赏。未来的计划旨在建立在这一成功的基础上，扩大与成瘾问题解决相关的临床转化研究的范围和影响。

DESCRIPTION (provided by applicant): This proposal seeks competitive renewal of a NIDA T32 grant (DA022981) to support the UAMS training program "Translational Training in Addiction." Initially funded in 2009, the program is designed to provide multi-level, transdisciplinary, team science training that spans the gamut of the molecular to community- based components of translational addiction research. Quantitative and qualitative data support the excellent outcomes of the current training plan. The proposed program plan extends the training goals to accomplish a state-of-the-art best practice approach to training the next generation of impacting addiction scientists across a broadening academic and non-academic workforce and basic and clinical research academic settings. Program evaluation is based on progress related to seven training objectives including (1) develop a shared knowledge of the scientific, clinical, and societal roles and impact of drug use disorders, (2) provide an individualized path of addiction research career development, (3) provide learning environments emphasizing interdisciplinary, team science, translational research, (4) provide grounding and training in research ethics and diversity, (5) remove barriers to independence and post-training placement, (6) monitor trainee and program progress, and (7) develop addiction physician-scientists. Program administration and management would be accomplished by coordinated interactions of the program Director, Steering Committee, and Governance Committee. Support is requested for four levels of trainees: 3 predoctoral, 4 postdoctoral, and 4 medical student summer interns. This will be complemented by the institutional support of a PGY3 psychiatry resident. Program-wide and track-selective didactics would support interdisciplinary T0 (molecular target identification)-T4 (implementation science) translational research training opportunities in broad academic as well as government addiction research settings emphasizing trainee-trainee and trainee-faculty interactions. Trainee and program success relative to career development milestones would be regularly monitored and evaluated. Barriers to career development would be addressed by a Path to Independence component of the program. Significant, multi- level institutional commitment and resources support the value and continued success of the program. A trainee-led Community Outreach component would educate and engage the local and state communities in addressing the problems of drug addiction. Based on 3+ years of program experience, the NIDA T32 training program at UAMS has accomplished its initial goals of effectively training demographically diverse and ethically conscious addiction researchers and placing trainees in competitive postdoctoral and faculty academic positions, as well as influencing the awareness and appreciation of addiction research by training physicians. The going forward plan seeks to build on this success and extend the scope and impact of clinical translational research related to addiction problem solving.