Cherokee Nation Health Analytics Core (CNHAC) Capacity Building Project

在美洲印第安人/阿拉斯加原住民（AI/AN）中，俄克拉荷马州的年龄调整发病率排名第五 1999-2012年美国任何癌症的死亡率（俄克拉荷马州为584.3/10万，美国为304.8/10万）， 美国的AI/AN在癌症生存率方面排名很低。此外，俄克拉荷马州在许多与健康有关的 与美国其他州相比，这些因素包括整体健康状况、癌症死亡率、缺乏医疗保险、 肥胖、缺乏运动和吸烟等可能与癌症发病率有关， 生存1997年，切罗基民族建立了第一个也是唯一一个部落经营的人口为基础的 国内监测流行病学和最终结果癌症登记处，包括癌症病例 居住在东北部14个县的切罗基民族部落管辖服务区（CNTJSA） 俄克拉荷马州。许多居住在CNTJSA的AI/AN在机构外接受癌症治疗。 切罗基民族卫生系统因此，CNCR需要与临床治疗和结果联系起来 来自切罗基国家卫生系统内外的卫生设施的数据，以获得广泛的关注- 行为和其他风险因素的信息。拟议的切罗基国家健康分析核心 （CNHAC）旨在通过以下具体目标进行能力建设： 切罗基民族和俄克拉荷马州健康科学中心大学公共卫生学院开发 CNHAC通过转换物理空间，雇用数据协调员，提供计算资源， 建立一个数据访问工作组; 2）制定访问和链接的政策和协议 来自各种卫生设施的电子健康数据，包括CNCR、切罗基国家EMR、OCCR和 MyHealth; 3）将CNCR记录与来自MyHealth的切罗基国家EMR和外部健康数据链接， 在未来的研究中使用; 4）使用以下针对乳腺癌的研究问题来测试 为临床数据用于研究的二次使用制定的政策和方案，并评估有效性， 数据链接的完整性：哪些因素影响对乳腺癌标准治疗的依从性 切罗基族妇女的治疗

Among American Indians/Alaska Natives (AI/AN), Oklahoma had the 5th highest age-adjusted incidence rate of any cancer in the US (584.3 per 100,000 in Oklahoma v. 304.8 per 100,000 in the US) from 1999-2012 and AI/ANs in the US rank poorly in cancer survival. In addition, Oklahoma ranks poorly in many health-related factors compared to other states in the US, including overall health, cancer mortality, lack of health insurance, obesity, physical inactivity, and smoking, among others, which may be related to cancer incidence and survival. In 1997, the Cherokee Nation established the first and only tribally-operated population-based Surveillance Epidemiology and End Results (SEER) cancer registry in the country, including cancer cases residing in the 14-county Cherokee Nation Tribal Jurisdictional Service Area (CNTJSA) in Northeastern Oklahoma. Many AI/ANs who reside in the CNTJSA receive treatment for their cancer at facilities outside of the Cherokee Nation health system. Thus, the CNCR needs to be linked with clinical treatment and outcomes data from health facilities both inside and outside of Cherokee Nation health system to obtain extensive follow- up and information on behavioral and other risk factors. The proposed Cherokee Nation Health Analytics Core (CNHAC) aims to build capacity by addressing the following specific aims: 1) Establish infrastructure at Cherokee Nation and the University of Oklahoma Health Sciences Center College of Public Health to develop the CNHAC through conversion of physical space, hiring data coordinators, providing computing resources, and development of a data access working group; 2) Develop policies and protocols for accessing and linking electronic health data from various health facilities including CNCR, Cherokee Nation EMR, OCCR, and MyHealth; 3) Link CNCR records with Cherokee Nation EMR and external health data from MyHealth to be used in future research studies; 4) Use the following research question focused on breast cancer to test the policies and protocols developed for secondary use of clinical data for research and to evaluate the validity and completeness of the data linkage: What factors influence adherence to standard of care for breast cancer treatment for women in Cherokee Nation?.