COBRE in CV Health Administrative Core

项目摘要/摘要 心血管疾病(CVD)，如心脏病、心力衰竭和中风，对特拉华州人的影响 明显高于全国平均水平。在这项申请中，我们寻求建立一个生物医学中心 心血管健康领域的卓越研究成果，可与更大区域的临床和研究对接 这是一项重大使命，并对我们区域人口的心血管健康产生积极影响。这个中心将催化 通过培养新子项目团队的独立研究职业生涯来进行心血管健康研究 研究人员，通过以下方式加强研究基础设施和执行心血管健康研究的能力 建立核心设施，以加强五个次级项目首席调查员的研究能力 和该中心的其他成员，并发展一个可持续的心血管健康研究中心。这个 Cobre管理核心的总体目标是最大限度地提高生产力和影响 通过有效的管理、指导和职业生涯，将子项目、核心和中心作为一个整体 中心的发展、评估和扩建。这将通过以下方式实现：1)建立有效的 管理拟议的Cobre的行政、财政和科学方面；2)建立 有效的指导和职业发展计划，以促进独立研究职业子项目NEW 调查人员；3)监测拟议的科布雷项目在实现里程碑方面的进展情况 实施总结性和形成性评价；以及4)通过试点赠款扩大该中心，以 新的研究人员和有针对性地招聘具有心血管健康专业知识的研究人员。 行政核心概述了一项领导计划，其中包括PI、内部咨询委员会和 评估员和即将成立的外部咨询委员会。一个指导计划，补充了 描述了在特拉华大学进行的指导。毕业和更替计划 还概述了子项目调查员的情况。

PROJECT SUMMARY/ABSTRACT Cardiovascular diseases (CVD) such as heart disease, heart failure, and stroke affect Delawareans at a rate significantly above the national average. In this application, we seek to establish a Center of Biomedical Research Excellence in Cardiovascular Health that can interface with the larger regional clinical and research mission and positively impact the cardiovascular health of our regional populations. This center will catalyze cardiovascular health research by fostering the independent research careers of a team of subproject new investigators, strengthen the research infrastructure and capacity to perform cardiovascular health research by establishing core facilities that will enhance the research capability of the five subproject principal investigators and other members of the Center, and develop a sustainable research center in cardiovascular health. The overall goal of the COBRE administrative core is to maximize the productivity and impact of each of the subprojects, core, and the center as a whole through effective management, mentoring and career development, evaluation, and expansion of the center. This will be accomplished by: 1) establishing effective management of administrative, fiscal, and scientific aspects of the proposed COBRE; 2) establishing an effective mentoring and career development plan to foster the independent research careers subproject new investigators; 3) monitoring the progress of the proposed COBRE toward milestones through the implementation of summative and formative evaluations; and 4) expanding the center through pilot grants to new investigators and targeted recruitment of research faculty with expertise in cardiovascular health. The administrative core outlines a leadership plan that includes the PI, an Internal Advisory Committee, an evaluator, and a to-be-formed External Advisory Committee. A mentoring program that complements the ongoing mentoring that occurs at the University of Delaware is described. Plans for graduating and replacing subproject investigators are also outlined.