2019 Myogenesis GRC/GRS

摘要 这项建议要求部分支持肌生成国际会议的一部分， 研究会议（GRC）和戈登研究研讨会（GRS）系列将在文艺复兴时期举行 2019年6月8日至14日，意大利卢卡（巴尔加）的托斯卡纳伊尔乔科。GRC肌生成国际会议 历史上被视为一个卓越的骨骼肌会议，吸引发言人， 来自世界各地的服务员。2019年会议的主要目标是扩大我们现有的知识 对细胞和分子机制，控制的形成，维护和再生， 骨骼肌。该领域的领导者将展示最近未发表的数据，以教育与会者 同时激发小组之间的互动讨论。GRC将邀请演讲者到GRC， 交流有关骨骼肌发育，稳态和 再生这些主题将通过九次科学会议进行交流，重点是： 维持骨骼肌（I&II）;卫星细胞与再生;骨骼肌的复杂性 结构;肌肉微环境的外在调节;肌肉细胞的内在信号传导; 肌生成的表观遗传、转录和转录后调控;细胞和分子 肌肉疾病的机制和关于肌肉发育的历史观点的主题演讲。在 此外，四场晚间海报会将促进所有与会者之间的互动。 GRS是一个为期两天的会议计划，针对研究生和博士后，立即发生 在GRC之前。GRS将举办四场研究生讲座和两场海报会议 和博士后研究员。 额外的计划活动将确保既定科学家和初级科学家之间的最大程度的互动 科学家/受训人员。其中包括海报展示会、2场“1分钟海报展示”， 为年轻科学家提供一个论坛，介绍他们的工作，并从其他参与者那里获得反馈， 专家早餐”、具体的社交活动和下午的非正式聚会。这些活动代表了 这是下一代科学家展示他们对肌生成的研究的独特机会， 他们的同行，并形成新的合作。 因此，我们预计2019年肌生成GRC将提供一个理想的场景，以刺激新的突破， 肌肉生物学，这将有利于与会者在每一个专业水平，并把外地在一个更好的位置 以加速肌肉生物学的进步，从而开发新的肌肉疗法。

ABSTRACT This proposal requests partial support for an international meeting on Myogenesis as part of the Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) series to be held at the Renaissance Tuscany Il Ciocco in Lucca (Barga), Italy June 8-14, 2019. The international meeting on GRC Myogenesis has historically been viewed as one of the preeminent skeletal muscle meetings, attracting speakers and attendants from around the world. The major goal of the 2019 Conference is to broaden our current knowledge on the cellular and molecular mechanisms that control the formation, the maintenance and the regeneration of skeletal muscle. Leaders in the field will present recent unpublished data to educate conference attendees while stimulating interactive discussion amongst the group. GRC will convene invited speakers to the GRC to exchange new information on the underlying mechanisms of skeletal muscle development, homeostasis and regeneration. These topics will be communicated through nine scientific sessions focusing on: Building and maintaining skeletal muscle (I&II); Satellite cells and regeneration; The complexity of skeletal muscle architecture; Extrinsic regulation of the muscle microenvironment; Intrinsic signaling in muscle cells; Epigenetic, transcriptional, and post-transcriptional regulation of myogenesis; Cellular and molecular mechanisms of muscular diseases and a keynote lecture on Historical perspective on muscle development. In addition, four evening poster sessions will stimulate interactions between all attendees. GRS is a two-day conference program targeting graduate students and postdocs that takes place immediately preceding the GRC. The GRS will conduct four sessions of talks and two poster sessions by graduate students and postdoctoral fellows. Additional program events will ensure maximal level of interaction between established scientists and junior scientists/trainees. They include poster sessions, 2 sessions of "1-minute poster presentation" that will provide a forum for junior scientists to present their work and receive feedback from other participants, "meet the experts breakfast", specific social events and informal gatherings in the afternoons. These activities represent a unique opportunity for the next generation of scientists to present their research on myogenesis, interact with their peers, and form new collaborations. Thus, we expect the 2019 Myogenesis GRC will provide an ideal scenario to stimulate new breakthroughs in muscle biology, that will benefit attendees at every professional level and to place the field in a better position to accelerate the advancement of muscle biology and thus the development of new therapies for muscle.