Socioeconomic status, stress, and smoking cessation

项目摘要/摘要 电子尼古丁递送系统(END)在成年人和 青少年和终端使用正在迅速成为一个主要的公共卫生问题。然而，由于他们最近 随着末端的出现，研究人员对末端、它们的用途、它们对人类生理和健康的影响、它们的 风险和利益，或其对烟草控制努力的影响。研究目的的一个常见障碍是缺乏 关于目标的客观、真实世界使用情况的数据。因此，拟议的项目旨在适应现有的创新移动 可用于通过提供移动感知来针对关键目标研究差距的评估工具 能够客观地实时收集有关终端在现实世界中使用的准确数据的技术。具体来说， 拟议的修订项目将扩大轨道项目(1R01CA190329-01A1，PI：WIDTER)的范围 扩展PuffMarker的应用程序，这是一个现有的自动检测吸烟的工具，用于评估 两端的使用率。当前的项目有三个目标：1)适配和验证PuffMarker以识别离散 Ends使用的几集，2)修改和验证PuffMarker以区分吸烟和Ends 在烟头和香烟的双重使用者之间使用，以及3)利用Project on Track协议进行实时采集， 调查排他性终端用户和 香烟和烟头的双重使用者。总共120名参与者(目标1 30人，目标2 30人，目标3 60人) 都会被录取。为AIMS 1和AIMS 2招募的参与者将参加实验室(三个2小时课程)和现场 (3天)学习。在实验室课程中，参与者将佩戴AutoSense无线传感器并 被要求使用烟头(目标1)或使用烟头吸烟(目标2)。参与者的烟头和香烟 喷雾将由独立的观察者记录下来。在实地研究中，参与者将佩戴AutoSense 使用无线传感器，并被要求使用末端(目标1)或使用末端和吸烟(目标2)。参与者 将被要求记录在SP上使用香烟或吸烟的每一次情况。该实验室的目标是 研究的目的是收集数据，训练吸烟者识别目的用途，并区分香烟 吸烟并最终使用。实地研究的目标是在现实生活中的自然环境中验证PuffMarker。 AIM 3将利用Project on Track协议收集第一个实时、真实的End和Dual数据 使用。参与者将使用AutoSense、EMA和GPS进行为期6天的评估，以检查潜力 最终用途的决定因素。一个经过验证的puffMarker，它检测End的使用并区分End 使用和吸烟可以加强对Ends的许多领域的研究。从目标3学到的知识将 对于开发有关最终用途和吸烟的综合概念模型至关重要 停止。

PROJECT SUMMARY/ABSTRACT The prevalence of electronic nicotine delivery systems (ENDS) is rising dramatically among both adults and youth and ENDS use is fast becoming a major public health issue. However, because of their recent emergence, researchers know little about ENDS, their use, their effects on human physiology and health, their risks and benefits, or their impact on tobacco control efforts. A common barrier to studying ENDS is the lack of data on objective, real world use of ENDS. Thus, the proposed project aims to adapt existing innovative mobile assessment tools that can be used to target critical ENDS research gaps by providing mobile sensing technology that can objectively collect precise data regarding ENDS use in real time in real world. Specifically, the proposed revision project will expand the scope of Project On Track (1R01CA190329-01A1, PI: Wetter) by extending the application of puffMarker, an existing tool that automatically detects smoking, for the assessment of ENDS use. The current project has three aims: 1) adapt and validate puffMarker to identify discrete episodes of ENDS use, 2) adapt and validate puffMarker to distinguish between cigarette smoking and ENDS use among dual users of ENDS and cigarettes, and 3) utilize the Project On Track protocol to collect real time, real world data investigating potential determinants of ENDS use among both exclusive ENDS users as well as dual users of cigarettes and ENDS. Altogether, 120 participants (30 for Aim 1, 30 for Aim 2, and 60 for Aim 3) will be enrolled. Participants recruited for Aims 1 and 2 will attend laboratory (three 2-hour sessions) and field (3 days) studies. In the laboratory sessions, participants will wear the AutoSense wireless sensors and be asked to use ENDS (Aim 1) or use ENDS and smoke a cigarette (Aim 2). Participants' ENDS and cigarette puffs will be recorded by an independent observer. In the field studies, participants will wear the AutoSense wireless sensors and be asked to use ENDS (Aim 1) or use ENDS and smoke cigarettes (Aim 2). Participants will be asked to record each instance of ENDS use or cigarette smoking on a SP. The goals of the laboratory studies are to collect data to train puffMarker to identify ENDS use and to distinguish between cigarette smoking and ENDS use. The goal of the field studies is to validate puffMarker in real-life, natural environments. Aim 3 will utilize the Project On Track protocol to collect the first real time, real world data on ENDS and dual use. Participants will be assessed for 6 days using AutoSense, EMA, and GPS to examine potential determinants of ENDS use. A validated puffMarker that detects ENDS use and distinguishes between ENDS use and smoking can enhance many areas of research inquiry on ENDS. Knowledge learned from Aim 3 will be essential for the development of comprehensive conceptual models with respect to ENDS use and smoking cessation.