Shared Resource: Population Studies Facility

计算/信息学共享资源：人口研究设施(PSF) 项目摘要/摘要 PSF在上次评审中被评为“杰出”。基于计算机的工具对许多研究来说是至关重要的 成功，特别是那些收集大量数据或涉及复杂数据收集协议的数据收集。这个 PSF通过提供关键的信息学基础设施和定制的、特定于项目的 癌症中心成员信息系统。PSF，由Eric Ross博士指导，拥有5.5名员工 FTE为成员提供稳定、经济高效的信息系统专业团队， 适合癌症研究的最先进的软件设计和工程技能。PSF功能包括 开发：用于存储和处理大量问卷、临床、 分子和标本数据.电子数据采集界面.报告生成软件.一致性和 质量控制系统；支持Web的多媒体应用程序；以及提供集成和 控制来自不同来源的数据交换。PSF是研究基础设施的关键组件 所有癌症中心的成员都可以随时访问。PSF已经开发了维护数据的系统 21万名研究对象。超过9万人在美国境内注册了fccc的研究；其余的人在 国际队列研究。PSF员工精通管理复杂数据库的软件工具和 精通合作调查人员使用的方法。从2011年到2014年，PSF提供了32,596 咨询时间，支持四个研究项目中的38名癌症中心成员。它提供了7125 2014年向24名癌症中心成员提供咨询时间。6380个咨询小时(90%)提供支持 由同行评议资助的癌症中心成员。PSF向其他七个联合国气候变化框架公约组织提供了直接信息学支持 CCSG在当前周期内支持的设施。PSF还与临床试验办公室合作 部署、定制和集成新的核心信息学工具以支持临床研究和 相关的监管职能。PSF在当前期间扩展了Fox Chase数据仓库(FCDW 周而复始。它现在集成了来自来自22.8万名患者和研究的41个研究和临床系统的数据 参与者。FCDW促进了翻译和相关的新合作和机会 研究。从2011年到2015年6月，方案规划编制局撰写了117份手稿，其中方案方案编制人员 合著者27。PSF可以访问广泛、最新的计算环境，其中包括开放的 源代码和商业软件工程工具。PSF由专门的设施咨询机构提供建议 每年开会的委员会(FAC)。来自FAC的建议被定向到一个管理机构 家长监督委员会(FPOC)，负责确保PSF继续拥有必要的 为癌症中心成员提供最高质量的信息服务的资源。对服务的需求 由于计划在所有5个研究计划和新计划中招聘，预计在下一个CCSG周期中将增加 TU癌症中心成员的需求。

COMPUTATIONAL/INFORMATICS SHARED RESOURCE: POPULATION STUDIES FACILITY (PSF) PROJECT SUMMARY/ABSTRACT PSF was rated "Outstanding" at the last review. Computer-based tools are vital to many research studies’ success, particularly those that collect large amounts of data or involve complex data collection protocols. The PSF facilitates FCCC research by providing critical informatics infrastructure and customized, project-specific information systems for Cancer Center members. PSF, with the direction of Eric Ross, PhD and a staff of 5.5 FTEs provides members with a stable, cost-effective team of information systems professionals with state-of- the-art software design and engineering skills appropriate to cancer research. PSF functions include development of: databases for the storage and manipulation of large quantities of questionnaire, clinical, molecular and specimen data; electronic data capture interfaces; report generation software; consistency and quality control systems; web-enabled multimedia applications; and systems that provide integration and controlled exchange of data from diverse sources. PSF is a critical component of the research infrastructure to which all Cancer Center members have ready access. PSF has developed systems that maintain data on over 210,000 subjects. More than 90,000 were enrolled in FCCC studies within the US; the remainder were in international cohort studies. PSF staff are proficient with software tools for managing complex databases and expert with methods employed by collaborating investigators. From 2011-2014, the PSF provided 32,596 consulting hours in support of 38 Cancer Center members in four Research Programs. It provided 7,125 consulting hours to 24 Cancer Center members in 2014. 6,380 of the consulting hours (90%) were in support of peer-review funded Cancer Center members. PSF provided direct informatics support to seven other FCCC CCSG-supported faciltiies during the current cycle. The PSF also collaborated with the Clinical Trials Office on deployment, customization and integration of new core informatics tools to support clinical research and associated regulatory functions. PSF expanded the Fox Chase Data Warehouse (FCDW) during the current cycle. It now integrates data from 41 research and clinical systems derived from 228,000 patients and study participants. The FCDW stimulates new collaborations and opportunities for translational and correlative research. From 2011 to June 2015, the PSF contributed to 117 manuscripts, of which PSF personnel are co-authors on 27. PSF has access to an extensive, up-to-date computing environment that includes open source and commercial software engineering tools. The PSF is advised by a dedicated Facility Advisory Committee (FAC) that meets annually. Recommendations from the FAC are directed to a governing Facility Parent Oversight Committee (FPOC) that serves to ensure that the PSF continues to have the necessary resources to provide the highest quality informatics services for Cancer Center members. Demand for services is expected to increase in the next CCSG cycle due to plans to recruit in all 5 Research Programs and new demand from Cancer Center members at TU.