2019 Aspen/Snowmass Perinatal Biology Conference

项目摘要 这项申请要求提供旅费，以便12名受训人员或新的调查员能够从 2019年白杨/Snowmass围产期生物学的6位受邀早期职业演讲者的美国和演讲者费用 会议美国围产期研究的长期传统支撑了我们对 胎儿发育的生理基础。将细胞和分子技术纳入研究， 在过去的20年里，人们已经深入了解了胎儿生理学的发育基础， 先兆子痫，IUGR，糖尿病和早产的病理生理学，与围产期相关的情况 发病率和死亡率。有一个新兴的认识，即子宫内的生命是与 成年期疾病的发展，即健康和成人疾病或胎儿疾病的发展起源 编程.这重新引起了人们对围产期生理学的兴趣。围产期研究界是 多学科;汇集了对母体、胎儿和胎盘感兴趣的临床医生和基础科学家 生理学和大量的农业动物科学家谁进行比较研究的伟大 与人类生理和发育的关系。它也有很强的传统，培训年轻的基础和 临床科学家他们的培训经验的一个重要组成部分是有机会在场地， 他们可以与资深科学家互动，并从榜样那里得到指导。本次会议将 来自母体、胎儿、胎盘和农业动物研究人员的专题介绍， “围产期暴露：导致发育结果的交叉机制”。会议将 为期3天半，包括新调查员在内的多个口头全体会议。全体会议将 同时举办几次互动讲习班，讨论青年面临的关键问题和挑战， 围产期生物学的研究者。将安排两场海报讨论会，并展示海报 为整个会议留出时间深入讨论工作。奖项将颁发给最佳海报 学员或新调查员的介绍。将根据审查选择受训人员和新的研究者 科学咨询委员会将对提交的第一作者摘要进行审查，以获得旅费。一直 在以前的会议上，女性与会者的比例一直很高（上次会议超过50%）， 本次会议的女发言人和会议主席人数众多。我们的少数族裔代表 15%，我们将继续努力提高这一数字，特别是指定最低为33% 请批预算中用于任职人数不足的少数族裔年轻调查员差旅费的部分。我们选择的场地 符合美国残疾人法案，并提供儿童保育和许多家庭活动 提供托儿服务，以方便所有人参加。

PROJECT SUMMARY This application seeks funding for travel costs to allow the attendance of 12 trainees or new investigators from the USA and speakers' fees for 6 invited early career speakers at the 2019 Aspen/Snowmass Perinatal Biology Conference. The longstanding tradition of perinatal research in the US underpins our knowledge of the physiologic basis of fetal development. Cellular and molecular techniques incorporated into investigation in the last 20 years have allowed in depth understanding of the developmental basis of fetal physiology and the pathophysiology of preeclampsia, IUGR, diabetes and premature delivery, situations associated with perinatal morbidity and mortality. There has been a burgeoning recognition that life in utero is associated with the development of disease in adult life, i.e. the developmental origins of health and adult disease or fetal programming. This has brought renewed interest in perinatal physiology. The perinatal research community is multidisciplinary; bringing together clinicians and basic scientists interested in maternal, fetal, and placental physiology and a substantial cadre of agricultural animal scientists who perform comparative studies of great relevance to human physiology and development. It also has a strong tradition of training young basic and clinician scientists. A vital part of their training experience is the opportunity to present work in venues where they can interact with senior scientists and receive the benefit of mentorship from role models. This meeting will feature presentations from maternal, fetal, placental and agricultural animal researchers around an integrated theme of “Perinatal Exposures: Intersecting Mechanisms leading to Developmental Outcomes”. The meeting will be 3 and 1/2 days with multiple oral plenary sessions including new investigators. Plenary sessions will be accompanied by several interactive workshop sessions addressing key questions and challenges facing young investigators in perinatal biology. Two poster discussion sessions are scheduled and posters will be displayed for the entire meeting to allow time for in-depth discussion of work. Prizes will be awarded for the best poster presentations by trainees or new investigators. Trainees and new investigators will be selected based on review of submitted first author abstracts by the Scientific Advisory Committee for award of travel funds. There has always been a high proportion (over 50% at our last meeting) of women attendees at previous meetings and women speakers and session chairs at this meeting are well represented. Our minority representation is around 15%, and we will continue efforts to improve this number, especially with the designation of a minimum of 33% of the requested budget used for travel by underrepresented minority young investigators. Our selected venue is compliant with the Americna's with Disabilities Act and also provides childcare and numerous family activities and available child care to facilitate attendance by all individuals.