Dissemination and Implementation Science in Cardiovascular Outcomes (DISCO)

项目总结/摘要 目标：本申请的目标是培训一批传播和实施（D&I）学者 从事T4翻译研究，使用严格的定性和定量方法来检查 采用、吸收、可接受性、可负担性、忠实性和可持续性， 建立了实施框架，以影响心脏、肺和血液疾病以及睡眠障碍。 研究职业发展计划的基本原理和设计：D&I学者的培训 研究涉及38名导师，他们在混合方法/评估、实用临床 试验、卫生服务研究/结果、卫生政策。导师们还在以下领域拥有具体的专业知识： 比如社区参与、健康差异、测量、流行病学、卫生经济学。每个 一名学者将至少有两名导师，其中至少一名来自研究方向，另一名来自特定的临床 焦点学者必须同时掌握知识和调查技能，并完成一系列工作 这足以证明他作为一名调查员的能力。这个计划是精心制定的， 学者获得成为独立调查员所需的技能。 培训计划中的关键活动。我们提供教学课程，包括具体的元素， 为这个项目设计的。本课程涉及的核心能力包括：（a）了解 传播和执行研究和评价所依据的理论和概念，包括混合 方法和准实验设计（例如，阶楔，自适应设计）;和（B）的知识， 研究设计和方法背后的理论和概念。我们强调成功使用的方法， 其他培训计划，以招募和选择学者，以及评估学者的进展和指导 经验和指导效果。 计划任用期：2-3年 预计奖学金获得者人数：5名 预期的学者成果：参加K12计划后，学者将有望获得 来自NIH或其他资助机构的年轻/新研究者或已建立的研究者奖。远程 目标是确保有足够的训练有素的研究人员来面对HLBS的临床问题 通过精心设计，巧妙地进行和多学科的临床研究。

Project Summary/Abstract Objectives: The goal of this application is to train a cohort of dissemination and implementation (D&I) scholars to engage in T4 translational research using rigorous qualitative and quantitative methods to examine the adoption, uptake, acceptability, affordability, fidelity, and sustainability of proven-effective interventions using established implementation frameworks to impact heart, lung, and blood diseases and sleep disorders (HLBS). Rationale and design of the research career development program: The training of scholars in D&I research involves 38 mentors with expertise in area such as mixed methods/evaluation, pragmatic clinical trials, health services research/outcomes, health policy. The mentors also have specific expertise in areas such community engagement, health disparities, measurement, epidemiology, health economics. Each scholar will have at least two mentors, with at least one from the research track and one from a specific clinical foci. Scholars must acquire both the knowledge and investigative skills as well as accomplish a body of work significant enough to demonstrate competence as an investigator. This program is carefully formulated to allow scholars to acquire the skills needed to become independent investigators. Key activities in the training plan. We provide a didactic curriculum that comprises elements specifically designed for this program. The core competencies addressed by this curriculum include: (a) knowledge of the theories and concepts underlying dissemination and implementation research and evaluation, including mixed methods and quasi-experimental designs (e.g., step-wedge, adaptive designs); and (b) knowledge of the theories and concepts underlying research designs and methods. We highlight methods used successfully for other training programs to recruit and select scholars as well as evaluate scholar progress and the mentoring experience and mentoring effectiveness. Planned duration of appointments: 2-3 years Projected number of scholars: 5 scholars Intended scholar outcomes: Following participation in the K12 program, scholars will be expected to obtain a young/new investigator or established investigator award from the NIH or another funding agency. Long-range goal is to ensure an adequate supply of well-trained researchers to confront the clinical problems HLBS medicine through well-designed, skillfully conducted and multidisciplinary clinical research.