Internet-based Motivational Interviewing for Colonoscopy in African Americans

 描述（由申请人提供）：与其他种族群体相比，非裔美国人的结直肠癌（CRC）发病率和死亡率最高。虽然结肠镜检查可以预防CRC，但近一半的非洲裔美国人（40.2%）没有在推荐的时间范围内接受结肠镜检查（每十年一次结肠镜检查）。提高非裔美国人的结肠镜筛查率以减少CRC发病率和死亡率的种族不平等是至关重要的。米勒博士的试点工作，以及目前的文献，表明基于互联网的动机访谈干预结肠镜检查（I-MIIC）可能有助于提高非裔美国人的筛查结肠镜检查的吸收。拟议的项目将首先使用迭代方法对干预措施进行现场测试，其中非洲裔美国人被推荐进行筛查结肠镜检查（N=40）。实地测试的结果将指导I-MIIC的开发、修订和定稿。然后，一项随机临床试验将检查-MIIC改善非裔美国人筛查结肠镜检查摄取的疗效。参与者（N=200）将被随机分配到一个干预组（N=100），其中他们参与20分钟的I-MIIC干预或对照组（N=100），其中他们审查CRC筛查的印刷手册。研究结果将有助于增加关于儿童权利委员会差异的文献。莎拉米勒博士是理想的候选人，带头这一系列的研究，因为她的学术和临床背景，在CRC的差距和动机面试。米勒博士的长期目标是成为一名独立的研究人员，在种族/少数民族癌症的早期发现和预防方面具有专业知识。为了实现她的目标，作为K 07的一部分，米勒博士将接受四个领域的强化培训：1）定性研究; 2）电子健康; 3）纵向数据分析; 4）专业发展。K 07将为米勒博士提供各种途径来实现她的培训目标并提高她的专业知识。特别是，米勒博士将与经验丰富的导师进行持续的会议，并参加正式的课程，研讨会，会议和互动培训。拟议的K 07将成为一项研究计划的基础，该计划的重点是改善少数种族/民族的癌症筛查率，以减少差异。在K 07资助期结束时，米勒博士将根据本研究的结果提交R 01申请。西奈山伊坎医学院（ISMMS）是米勒博士完成她提出的研究项目和培训的理想环境。特别是，ISMMS可以为米勒博士提供：1）完成研究所需的资源; 2）参加多种培训活动; 3）接触多样化的患者群体。最重要的是，米勒博士将接受一个上级导师团队的指导，他们在以下方面具有专业知识：CRC差异，定性研究，生物统计学，电子健康和初级保健。指导小组将与米勒博士密切合作，以确保她实现她的研究和培训目标。总的来说，K 07将为米勒博士提供成为一名成功的独立研究人员所需的研究经验、强化培训和指导。

 DESCRIPTION (provided by applicant): Compared to other racial groups, African Americans have the highest colorectal cancer (CRC) morbidity and mortality rates. Although colonoscopies can prevent CRC, nearly half of African Americans (40.2%) have not received a screening colonoscopy within the recommended time frame (one colonoscopy per ten years). It is critical to increase African Americans' screening colonoscopy rates in order to reduce racial inequities in CRC morbidity and mortality. Dr. Miller's pilot work, as well as the current literature, suggest that an Internet-based Motivational Interviewing Intervention for Colonoscopy (I-MIIC) may help improve African Americans' screening colonoscopy uptake. The proposed project will first field-test the intervention, using an iterative approach, with African Americans referred for a screening colonoscopy (N=40). The field-testing results will guide the development, revisions, and finalization of the I-MIIC. Then, a randomized clinical trial will examine the efficacy of the -MIIC for improving African Americans' screening colonoscopy uptake. Participants (N=200) will be randomly assigned to an intervention group (N=100) in which they engage in a 20-minute I-MIIC intervention or a control group (N=100) in which they review a print brochure on CRC screening. The results will contribute to the growing literature on CRC disparities. Dr. Sarah Miller is the ideal candidate to spearhead this line of research given her academic and clinical background in CRC disparities and motivational interviewing. Dr. Miller's long-term goal is to become an independent researcher with expertise in the early detection and prevention of cancer in racial/ethnic minorities. To achieve her goals, as part of the K07, Dr. Miller will receie intensive training in four areas: 1) qualitative research; 2) e-Health; 3) longitudinal data analyss, and 4) professional development. The K07 will provide Dr. Miller with a variety of avenues to achieve her training goals and enhance her expertise. In particular, Dr. Miller will have ongoing meetings with seasoned mentors as well as participate in formal coursework, workshops, conferences, and interactive trainings. The proposed K07 will form the foundation for a program of research that focuses on improving cancer screening uptake in racial/ethnic minorities with the goal of reducing disparities. At the end of the K07 funding period, Dr. Miller will submit an R01 application, based on the results of the present study. The Icahn School of Medicine at Mount Sinai (ISMMS) is the ideal environment for Dr. Miller to complete her proposed research project and training. In particular, the ISMMS can offer Dr. Miller: 1) the resources necessary to complete her research; 2) access to multiple training activities; and 3) access to a diverse patient population. Most importantly, Dr. Miller will receive guidance from a team of superior mentors with expertise in: CRC disparities, qualitative research, biostatistics, e-Health, and primary care. The mentoring team will work closely with Dr. Miller to ensure that she achieves her research and training objectives. Overall, the K07 will provide Dr. Miller with the research experience, intensive training, and mentorship needed to become a successful independent researcher.