Sculpted Light in the Brain Conference

项目摘要 神经科学因两种实验方法的广泛采用而发生了革命性的变化：光遗传学， 光被用来控制神经活动，钙成像，光被用来监测神经活动。 “大脑中的雕塑光”指的是改变光的形状以使之更有用的光学过程 既有成像又有刺激的目的，是本次大会的一个根本主题。随着……的到来 这些方法传统的电记录和刺激工具正在逐步地 作为补充，有时还被这些基于光的方法所取代。然而，仍然需要取得进展。 使这些光学技术达到了解神经活动所需的速度、特异性和范围。 这次会议是及时的，因为新一代先进的基于光的生物工具从根本上说是 改变神经科学家询问神经系统的方式，依赖于计算和 光学方法与神经科学。 2017年会议的成功凸显了这一议题的及时性。《大脑中的雕刻之光2017》是 最初设计为加州大学伯克利分校的一个简短(1天)的本地会议。然而，由于 由于组织者的极大兴趣以及参与和承诺，2017年会议是 在14个实体的资助下，迅速扩大到11名发言者(3名国际发言者)。反馈是 绝大多数是积极的，会议在神经光子学中得到了强调(Shanker等人，2017年)。这个 2019年大脑雕刻之光会议的项目是由一个跨学科的、国际的 委员会根据实地提出的建议进行指导。组织者包括来自2017年组织的3名科学家 3名新成员，包括2名妇女和2名国际代表。 本次会议将通过聚集知名科学家和下一代科学家来创造未来的合作机会 来自光学、计算机科学和神经科学领域的一代研究人员在讨论 专注于开发未来的基于光的技术，使之能够与生物进行实时交流 大脑。这一具有前瞻性的独特的新会议满足了科学界的迫切需求，即 目前完全没有得到满足，因为没有其他直接致力于这一迅速的独立会议 不断增长的科学领域。

Project Summary Neuroscience has been revolutionized by the widespread adoption of two experimental methods: optogenetics, where light is used to control neural activity, and calcium imaging, where light is used to monitor neural activity. ‘Sculpted Light in the Brain’ refers to the optical process of changing the shape of light to be more useful for both imaging and stimulation purposes, and is a fundamental theme of this conference. With the advent of these approaches conventional electrical recording and stimulation tools are being progressively complemented and sometimes replaced by these light-based approaches. However, progress is still needed for these optical techniques to reach the speed, specificity, and range necessary to understand neural activity. This meeting is timely since this new generation of advanced light-based biological tools is fundamentally transforming how neuroscientists interrogate the nervous system, relying on the fusion of computational and optical methods with neuroscience. The success of the 2017 meeting highlights the timely nature of this topic. Sculpted Light in the Brain 2017 was originally designed as a brief (1 day) local conference at University of California at Berkeley. However, due to overwhelming interest as well as the engagement and commitment of the organizers, the 2017 meeting was rapidly expanded to 11 speakers (3 international) supported by funding from 14 entities. Feedback was overwhelmingly positive, and the conference was highlighted in Neurophotonics (Shanker et al 2017). The programs for the 2019 Sculpted Light in the Brain meeting was designed by an interdisciplinary, international committee guided by suggestions from the field. The organizers include 3 scientists from the 2017 organization committee, and 3 new members, including 2 women and 2 international representatives. This meeting will generate future collaboration opportunities by gathering established scientists and the next generation of researchers from the fields of optics, computer science, and neuroscience in a discussion focused on developing future light-based technologies that will enable real time communication with the living brain. This forward-looking unique new conference satisfies an urgent need in the scientific community that is currently completely unmet, since there are no other stand alone meetings directly dedicated to this rapidly growing scientific area.