Southeast Collaborative Alliance for Stroke Trials (SE-CoAST)

中风的负担继续不成比例地影响着美国东南部-所谓的 冲刺腰带。为这些人群提供中风教育、预防、急性治疗、康复和 尤其是参与临床研究，仍然是一个挑战。开发一种高功能的临床和 研究多中心基础设施，让这些中风高危人群参与进来，对于改变 不成比例的中风负担。 中风护理和研究，从预防，到急性治疗，最后到康复/ 康复，最好是在多学科医疗团队的背景下提供和执行。卒中 医疗保健系统整合了一个地理区域的医疗资源，被公认为最佳 实践，确保区域内的最佳护理。研究也最好是在现有的 临床卒中护理系统，利用调整领域--患者教育、参与、卒中 医疗保健社区的认识，以及所有人对研究参与机会的认识 医疗保健设置。 在该应用中，扩展的东南卒中试验协作联盟(东南海岸)及其 调查人员仍致力于作为StrokeNet的区域协调中心。东南海岸现在是 位于中心的4个三级医疗学术医疗中心之间的扩展、强大的合作 中风带：南卡罗来纳州沿海的南卡罗来纳医科大学，东部的奥古斯塔大学 佐治亚州，南卡罗来纳州北部的格林维尔健康系统和棕榈树健康/南卡罗来纳大学 南卡罗来纳州中部的卫生系统。这个扩大的网络最大的优势是我们现有的 在研究和中风护理提供方面的合作伙伴关系。东南海岸现在几乎覆盖整个南卡罗来纳州和一个 很大比例的GA，考虑到我们的集水区的广度以及我们重要的远程通话存在 在东南部。东南海岸的总体目标仍然是：1)利用东南海岸组织 增加我们各州参与急性、预防和恢复性中风网试验的居民人数； 2)继续我们在全国StrokeNet活动中的领导角色；3)利用东南海岸的临床前 研究人员正在开发有前景的治疗干预措施，以便在卒中网络内进行研究；4)继续 支持和促进我们StrokeNet学者的职业发展。

The burden of stroke continues to disproportionately impact the Southeast United States – the so-called Stroke Belt. Reaching these populations for stroke education, prevention, acute treatment, rehabilitation, and in particular participation in clinical research, remains a challenge. Developing a highly functional clinical and research multicenter infrastructure to engage these populations at high risk for stroke is critical to change the disproportionate stroke burden. Stroke care and research, from prevention, through acute treatment, and finally through recovery / rehabilitation, are best provided and performed in the context of multidisciplinary healthcare teams. Stroke Systems of Care, integrating healthcare resources across a geographic region, are recognized as best practice, ensuring optimal care within the region. Research is also best performed working within the existing clinical stroke systems of care, capitalizing on areas of alignment – patient education, engagement, stroke awareness in the healthcare community, and awareness of research participation opportunities in all healthcare settings. In this application, the expanded Southeast Collaborative Alliance for Stroke Trials (SE-CoAST) and its investigators remain committed to serving as a Regional Coordinating Center in StrokeNet. SE-CoAST is now an expanded, robust collaboration between 4 tertiary care academic medical centers situated in the heart of the Stroke Belt: the Medical University of South Carolina along the SC coast, the Augusta University in eastern GA, the Greenville Heath System in the upstate of SC, and the Palmetto Health / University of South Carolina Health System in the midlands of SC. The greatest strength of this expanded network is our existing partnerships in research and stroke care delivery. SE-CoAST now serves nearly the entire state of SC and a large proportion of GA, given the breadth of our catchment areas as well as our significant telestroke presence across the Southeast. The overall goals of SE-CoAST remain: 1) to leverage the SE-CoAST organization to increase the number of residents of our states participating in acute, prevention and recovery StrokeNet trials; 2) to continue our leadership roles in StrokeNet activities nationally; 3) to utilize SE-CoAST preclinical researchers in developing promising therapeutic interventions for study within StrokeNet; 4) to continue to support and enhance the career development of our StrokeNet scholars.