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Advances in Sleep and Circadian Science

Advances in Sleep and Circadian Science
睡眠和昼夜节律科学的进展
批准号:
9763135
负责人:
Martica Helon Hall
金额:
$1.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-02-01 至 2020-01-31

项目摘要

项目成果

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中文摘要
翻译
睡眠研究协会(SRS)致力于促进和推进对睡眠的科学理解。 睡眠和昼夜节律的翻译谱,从他们的分子调控跨物种, 通过遗传、表观遗传、文化和社会力量的跨代传递, 以及对健康和功能的长期影响。睡眠和昼夜节律之间存在着不可分割的联系, 维持对生存至关重要的生理和行为过程,如细胞老化和修复,进食 和新陈代谢,学习和记忆,以及联系和情绪调节。2017年,生物学家 Michael W. Young,Michael Rosbash,and Jeffrey C.霍尔被授予诺贝尔生理学奖或 他们的发现推动了我们对控制癌症的分子机制的理解, 昼夜节律昼夜节律的分子基础方面的进展反过来又为我们提供了信息, 了解睡眠的细胞和分子机制。因为睡眠和昼夜节律领域 科学在某种程度上是独立发展的,它们的范围和范围将受益于各种机会, 交流思想和方法。SRS试图组织一个独特的睡眠和昼夜节律科学会议, 促进讨论前沿科学,找出我们知识的差距,并促进新的合作, 跨学科研究睡眠和昼夜节律科学会议的单一轨道进展将包括 研究,桥梁,或有很大的潜力,桥梁,基础和翻译睡眠和昼夜节律科学。 科学会议的重点是整个生命周期的睡眠和昼夜节律的控制和输出。 主题包括分子调节、神经和外周回路、代谢、发育、衰老和 稳态睡眠和昼夜节律的神经变性,以及它们对认知的调节, 动机和影响。这次会议的关键组成部分是专门的方案拟订和指导 培训生和早期研究人员(ESI)的机会,他们代表了这一重要领域的未来。 跨学科领域正如我们的具体目标和会议计划中所详细说明的那样,本SRS R13的总体目标 是为学员和ESIs提供差旅支持,以参加并积极参与这一开创性会议。 睡眠和昼夜节律科学学者奖将为竞争性选择的学员提供旅行支持 谁提交摘要提出海报,并被判定为表现出杰出的潜力, 从事跨学科睡眠和昼夜节律科学的研究。睡眠和昼夜节律科学机会奖 将向来自科学领域代表性不足的群体的学员提供旅行支持,尽管他们在早期 培训管道,表达对睡眠和昼夜节律科学的兴趣。睡眠与昼夜节律科学 整合奖将帮助支付会议费用的有前途的ESI的工作考虑到睡眠, 昼夜节律
英文摘要
The Sleep Research Society (SRS) is dedicated to promoting and advancing the scientific understanding of sleep and circadian rhythms across the translational spectrum, from their molecular regulation across species, to their cross-generational transmission through genetic, epigenetic, cultural, and social forces, to their acute and longer-term impact on health and functioning. Inexorably linked, sleep and circadian rhythms entrain and sustain physiological and behavioral processes critical to survival, such as cellular aging and repair, feeding and metabolism, learning and memory, and affiliation and emotion regulation. In 2017, circadian biologists Michael W. Young, Michael Rosbash, and Jeffrey C. Hall were awarded the Nobel Prize in Physiology or Medicine for their discoveries that propelled our understanding of the molecular mechanisms controlling circadian rhythms. Advances in the molecular underpinnings of circadian rhythms have, in turn, informed our understanding of the cellular and molecular mechanisms of sleep. Because the fields of sleep and circadian science have evolved somewhat independently, their reach and scope would benefit from opportunities to exchange ideas and methods. The SRS seeks to organize a unique sleep and circadian science meeting to promote discuss cutting-edge science, identify gaps in our knowledge, and catalyze new collaborations in transdisciplinary research. The single-track Advances in Sleep and Circadian Science meeting will include research that bridges, or has great potential to bridge, basic and translational sleep and circadian science. Scientific sessions are focused on the control and outputs of sleep and circadian rhythms across the lifespan. Topics include molecular regulation, neural and peripheral circuits, metabolism, development, aging and neurodegeneration of homeostatic sleep and circadian rhythms, as well as their regulation of cognition, motivation, and affect. Critical components of this meeting are specialized programming and mentoring opportunities for trainees and early stage investigators (ESIs), who represent the future of this important transdisciplinary field. As detailed in our Specific Aims and Conference Plan, the overall goal of this SRS R13 is to provide travel support for trainees and ESIs to attend and actively take part in this pioneering meeting. Sleep and Circadian Science Scholar Awards will provide travel support to competitively-selected trainees who submit an abstract to present a poster and are judged to show outstanding potential for a productive career in transdisciplinary sleep and circadian science. Sleep and Circadian Science Opportunity Awards will extend travel support to trainees from groups underrepresented in science who, although early in the training pipeline, express an interest in sleep and circadian science. Sleep and Circadian Science Integration Awards will help defray conference costs for promising ESIs whose work considers sleep and circadian rhythms.
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会议论文
Major Depression and Molecular Senescence: The Role of Sleep
Conference grant application to support American Psychosomatic Society's 75th Annual Scientific Meeting
Sleep: A Novel Pathway Linking Major Depression and Cardiovascular Disease
Sleep: A Novel Pathway Linking Major Depression and Cardiovascular Disease
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