Accelerated public health and biomedical research on priority public health objectives through collaboration between US NIH and WHO

摘要 世界卫生组织(世卫组织)是全球卫生事务的牵头机构。它满足了一个 制定全球卫生规范和标准以及在提供技术支持方面的双重任务 向成员国提供援助。最近，世卫组织在卫生紧急情况下采取的行动 被强调为一项重要的额外优先事项。健康研究是一个重要的 它在所有工作领域的作用，其在研究中的作用最近得到了 世界卫生大会。 为实现与研究有关的目标，世卫组织与 世界各地的政府和其他研究机构，如 世卫组织合作中心网络。世卫组织与BREADD一起处理研究项目组合 对美国国立卫生研究院专门机构目标的补充，涵盖传染病和非传染性疾病 传染病、地方性疾病、流行病以及新出现的健康威胁。美国国立卫生研究院AS 它是生物医学研究的全球领先者，也是世卫组织推动知识进步的关键合作伙伴 基地和开发新的药物干预措施。 这项建议旨在加强两个机构之间的合作，以增加 支持最紧迫的公共卫生的研究的相关性、效率和覆盖范围 需要。 这将通过结合两个组织独特的创新方法来实现， 基于NIH在医学和生物医学研究方面的卓越表现，以及它获得大量 研究基础设施，以及世卫组织的全球影响、其规范作用和在 与实施科学的关系。 这项合作将利用世卫组织广泛的研究方案经验，其 有能力召开会议并制定议程，并通过透明和 包容性协商进程，考虑到所有相关区域和社区， 以及评估世卫组织的分散结构。先前的工作已经证明了这种力量 这种方法的一部分。 具体目标是双重的，涵盖#年新出现的问题领域的协作行动 需要对基础研究、转化研究和实施研究进行投资的公共卫生； 和一个具体的目标是促进虫媒病毒疾病的工作从基础到翻译和 实施相关研究。协作有很大的扩展空间 支持这两个机构的活动有共同的目标和目的。

Abstract The World Health Organization (WHO) is the global lead agency in health matters. It fulfils a dual mandate of developing global norms and standards in health, and in providing technical assistance to member countries. More recently, WHO’s action in health emergencies has been highlighted as an important additional priority. Health research is an important component across all areas of work, and its role in research has recently been re-affirmed by the World Health Assembly. To achieve its objectives related to research, WHO maintains effective collaboration with governmental and other research organizations throughout the world, as evidenced by the network of WHO Collaborating Centres. WHO addresses a research portfolio with broad complementarity to the goals of NIH specialized institutes, covering communicable and non- communicable diseases, endemic, epidemic as well as emerging health threats. NIH as global leader in biomedical research, it is a key partner for WHO in advancing the knowledge base and in the development of new medicinal interventions. This proposal aims at enhancing collaboration between the two agencies to increase relevance, efficiency and reach of the research in support of the most pressing public health needs. This will be achieved by combining unique innovative approaches of both Organizations, building on NIH’s excellence in medical and biomedical research and its access to a vast research infrastructure, and on WHO’s global reach, its normative role and excellence in relation to implementation sciences. The collaboration will make use of WHO’s broad research programme experience, its capacity to convene and set agendas, and to develop consensus through transparent and inclusive consultative processes, with consideration of all relevant regions and communities, and taking stock of WHO’s decentralized structure. Prior work has demonstrated the power of this approach. Specific aims are dual, and cover collaborative action in the area of emerging issues in public health that require investments in basic, translational and implementation research; and a specific aims to promote work on arboviral diseases from basic to translational and implementation related research. There is significant room for expansion of collaborative activities in support of both institutions shared goals and objectives.