Mapping in Atrial Fibrillation: A 3-dimensional Electrophysiological Evaluation of the Electro-pathological Substrate

房颤是最常见的心律失常。然而，这种疾病进行性的潜在机制仍然知之甚少。本研究旨在研究心房颤动易发条件下的三维电离及其与病理变化的关系。这些知识将促进针对房颤的个体化、底物导向的药物治疗和有针对性的治疗程序的发展。

Atrial fibrillation is the most frequently encountered heart rhythm disorder. However, mechanisms underlying the progressive nature of this disease remain poorly understood. This study aims to characterize the 3-D electrical dissociation and its relation to pathological changes in conditions predisposing to atrial fibrillation. This knowledge will facilitate the development of individualized, substrate-oriented pharmacological treatment and targeted therapeutic procedures for atrial fibrillation.