Maternal-Fetal Medicine Units Network -- The Northwestern Study Center

 描述(申请人提供)：在美国，每年约有400万名新生儿出生，分娩是住院治疗的主要适应症。因此，预防包括早产和产妇发病率在内的产科不良后果是一个重要目标，而旨在改善产科结局的临床试验和观察性研究至关重要。通过建立一个多机构的研究基础设施，母婴医学单位网络是有效实现这一目标的重要机制。西北大学研究中心通过使用创新的招聘技术和研究设计方法，自2001年以来一直是MFMU网络的富有成效的成员，并由在MFMU网络中合作了10多年的两个机构组成：西北大学和北岸大学卫生系统。此外，这两个机构的两个母胎医学部在其他多项临床研究和试验方面有长期和持续的合作。在这份提案中，我们提出了西北研究中心重新加入MFMU网络的申请。在经验丰富的临床研究人员团队(威廉·格罗布曼医学硕士、艾伦·皮斯曼医学博士、医学硕士玛拉·丁斯莫尔医学硕士、盖尔·马莱特RN)的带领下，西北研究中心将继续为MFMU网络的目标做出重要贡献，因为它将大力招收不同社会经济背景的患者，并致力于新研究的概念和开发。

 DESCRIPTION (provided by applicant): In the United States, there are approximately 4 million births per year and childbirth is the leading indication for hospitalization. Correspondingly, the prevention of adverse obstetric outcomes, including preterm birth and maternal morbidity, is an important goal, and clinical trials and observational studies designed to improve obstetric outcomes are of the utmost importance. The Maternal-Fetal Medicine Units (MFMU) Network, by creating a multi-institutional research infrastructure, is an important mechanism to accomplish this goal effectively. The Northwestern Study Center, through its use of innovative recruitment techniques and study design approaches, has been a productive member of the MFMU Network since 2001, and is composed of two institutions that have worked together in the MFMU Network for over 10 years: Northwestern University and NorthShore University Health System. The two Maternal-Fetal Medicine Divisions of the institutions, in addition, have a long and continuing collaboration on multiple other clinical research studies and trials. In this proposal, we present the application of the Northwestern Study Center to renew its participation in the MFMU Network. Led by a team of experienced clinical researchers (William Grobman, MD, MBA; Alan Peaceman, MD; Mara Dinsmoor, MD, MPH; Gail Mallett, RN), the Northwestern Study Center will continue its significant contributions to the MFMU Network's goals though robust enrollment of socioeconomically diverse patients and the conception and development of novel studies.