Efficient diagnostic tools to evaluate central auditory dysfunction

 描述(由申请人提供)：大多数听力损失的诊断都集中在听力图上，听力图对与听觉感知相关的许多额外处理阶段的功能障碍不敏感。例如，最近来自许多实验室的数据，包括我们自己的，都显示出明显的听觉处理缺陷，无论是在老年听众还是遭受创伤性脑损伤的患者，尽管听力图正常。现代听神经科学、计算模型和心理声学为听觉感知的信息处理提供了极大的洞察力，并确定了用于评估中枢听觉功能的特定刺激和任务，但这些信息在很大程度上仍停留在实验室。这项建议的目标是开发和评估一套临床测试，这些测试借鉴了现代实验室测试和听觉系统功能理论。这些将构成一种新的中枢听觉功能障碍临床测试组件的基础，该组件将支持对可能导致听觉主诉的更广泛困难的准确诊断。

 DESCRIPTION (provided by applicant): Most diagnoses of hearing loss focus on the audiogram, which is not sensitive to dysfunction at many of the additional processing stages associated with auditory perception. For example, recent data from many laboratories, including our own, have shown clear auditory processing deficits both in older listeners and in patients who have suffered traumatic brain injury, despite normal audiograms. Modern auditory neuroscience, computational modeling, and psychoacoustics have provided great insight into the information processing that underlies auditory perception and have identified specific stimuli and tasks for the evaluation of central auditory function, but this information has largely remained in the laboratory. It is the goal of this proposal to develop and evaluate a set of clinicl tests that draw upon modern laboratory tests and theories of auditory system function. These will form the basis of a new clinical test battery for central auditory dysfunction that will suppot the accurate diagnosis of a much wider range of the difficulties that can lead to auditory complaints.