Test-Retest Reliability of Micro and Macro Linguistic Measures in People with Aphasia and Healthy Adults During Conversation and Narrative Discourse

项目摘要 失语症患者(PWA)及其家人表示，恢复与他人交谈的能力是 他们最大的康复目标。尽管对话在日常生活的方方面面都至关重要， 不存在专门针对对话的基于研究的语言干预。对发展至关重要 是衡量语言产生变化的相关和可靠的方法 对话级别。因此，为了满足这一需求，本项目的广泛、长期目标是确定哪些 微观和宏观语言测量是测量PWA会话中语言技能的可靠工具。 此外，这项研究将提供适当临床使用这些措施所需的知识(即， 在叙事和会话语篇语境中每种衡量标准的关系)和适当的 解释(即对健康成年人(HA)功能的理解)三项措施预计不会达到 这项研究的结果将对公共卫生产生影响，因为它提供了 对失语症的全面评估，包括会话水平的话语。此外，公共卫生将是 受影响是因为这项研究的结果将使亟需的相关、有效的开发 专门针对谈话的治疗，对健康、福祉和独立的恢复至关重要 在PWA。这项研究直接属于NIDCD 2017-2021年战略计划的范围。这个 研究将提供满足研究需要的数据，以扩展知识基础以了解 功能性交流需求(对话)范围内的正常功能和功能障碍(失语症)， 同时提供可影响诊断和治疗并改善总体结果的基础知识 在人类交流方面，NIDCD所述的目标。将使用小组研究设计来解决以下问题： 具体目标1：评价微观语篇和语篇层面话语测量的重测信度 非结构化对话中PWA和HA的宏观语言技能和交际成功 两位不熟悉的言语病理学家合作伙伴在治疗PWA(SLP-Ps)方面有经验。 具体目标2：评估PWA组和匹配组之间是否存在显著差异以及差异程度 在与SLP-P的对话中，HA组对信息性、全球凝聚力和CS的三个指标进行了测试。 具体目标3：评估非结构化对话中每项衡量标准的重要性和相关性程度 PWA中的话语和结构化叙事(通过无字图画书讲故事)。 这项研究将在丽莎·埃德蒙兹博士的失语症研究和教师双语实验室进行 学院，哥伦比亚大学，一个提供空间、设备、广泛的研究图书馆的环境， 材料，以及智力对话的机会。拟议的培训计划旨在提供 作为一名独立研究员，她需要更多的经验和对独立研究人员的支持。

Project Abstract People with aphasia (PWA) and their families indicate that regaining the ability to converse with others is one of their greatest rehabilitation goals. Despite the critical importance of conversation in every facet of daily life, research-based language interventions aimed specifically at conversation do not exist. Critical to development of such intervention are relevant and reliable methods to measure change in language production at the conversation level. Thus, to meet this need, the broad, long-term the goals of this project are to determine which micro and macrolinguistic measures are reliable for use in measuring linguistic skills in conversation in PWA. Further, this research will provide knowledge required for appropriate clinical use of the measures (i.e., relationship of each measures in narrative and conversational discourse contexts) and for appropriate interpretation (i.e. understanding of functioning of healthy adults (HA) for three measures not expected to be at ceiling).The findings of this study will have public health impact by providing foundational knowledge needed for comprehensive assessment of aphasia that includes conversation-level discourse. Further, public health will be affected because the findings of this research will permit the much-needed development of relevant, effective treatment specifically directed to conversation, crucial to the health, well-being and recovery of independence in PWA. This research is situated directly within the scope of the NIDCD’s Strategic Plan for 2017-2021. The study will provide data meeting the need for research that extends the knowledge base in the understanding of normal function and dysfunction (aphasia) within the domain of a functional communication need (conversation), while providing foundational knowledge that can impact diagnosis, and treatment, and improve overall outcome for human communication, stated goals of the NIDCD. A group study design will be used to address: Specific Aim 1: Evaluate the test-retest stability of word- and utterance level discourse measures of micro and macrolinguistic skills and communicative success (CS) in PWA and HA during unstructured conversations with two unfamiliar Speech Language Pathologist partners experienced in working with PWA (SLP-Ps). Specific Aim 2: Evaluate presence and extent of significant between group differences for PWA and matched HA groups for three measures of informativeness, global cohesion and CS in conversation with an SLP-P. Specific Aim 3: Evaluate significance and extent of correlation of each measure in unstructured conversational discourse and structured narrative (story-telling via wordless picture book) in PWA. This research will be conducted in Dr. Lisa Edmonds’ Aphasia Research and Bilingualism Lab at Teachers College, Columbia University, an environment providing space, equipment, an extensive research library, materials, and opportunity for intellectual dialogue. The proposed training plan is designed to provide experiences and support to the PI needed to further her development as an independent researcher.