Administrative Core

核心A：行政 摘要 管理核心（核心A）是宾夕法尼亚大学创新，有影响力的研究企业背后的引擎 CFAR是宾夕法尼亚大学、费城儿童医院和Wistar研究所的合作项目。 在本周期中，CFAR调查人员在艾滋病优先领域取得了重大发现，包括 HIV治疗，由Martin Delaney合作实验室资助;淋巴内免疫控制的性质 库;令人兴奋的新疫苗平台和模型;艾滋病毒合并感染和合并症;多维 改进艾滋病毒预防和护理连续体参与的方法;以及其他关键主题。核心 A推动CFAR战略规划流程，提供科学领导，以确定和推出新的 研究方向，并监督其科学工作组的建立和活动。核心 A监督CFAR的七个共享资源核心;其发展核心;其教育，指导， 外展和合作活动;以及进一步加强与费城校园紧密联系的举措 社区以及地方、国家和国际伙伴。核心A还提供校园领导， 确保机构支持，优先考虑艾滋病研究和教师招聘的伙伴关系， 和CFAR调查人员之间的沟通，以维持一个合作，互动的研究社区。 核心A领导层于2年前过渡，由罗纳德科尔曼博士（主任）和罗伯特格罗斯（副主任）领导。 主任），Kathleen布雷迪博士作为核心研究者加入。核心A与管理执行人员密切合作 委员会，以及内部咨询委员会，外部咨询委员会和社区咨询委员会。 核心A的目标是（1）部署CFAR资源和活动，以促进当前和未来的研究， 通过科学工作组、跨学科合作和核心活动， （2）提供行政领导，确保各部门之间的有效沟通; 所有CFAR组成部分和成员，领导一个强大的和包容性的战略规划过程， 支持，并支持招聘优秀的艾滋病毒/艾滋病研究人员到校园;（3）监督CFAR的 共享资源核心，以确保它们提高研究能力，满足CFAR调查人员的需求， 引入新的使能技术和专业知识，推动研究议程并支持CFAR SWG; (4)确保对CFAR核心、发展基金和机构资源进行健全的财政管理;（5） 建立和监督多学科教育、辅导和外联活动， 促进受训人员和初级教师的科学发展，建立伙伴关系， 调查员进入现场，并促进CFAR活动和领导作用的多样性和包容性;（6） 确保CFAR与受艾滋病毒/艾滋病影响的当地社区充分合作， 包括费城公共卫生部在内的组织利用并促进了Inter-CFAR 国家网络，并率先与国际合作伙伴开展强有力的合作和能力建设活动。

Core A: Administrative ABSTRACT The Administrative Core (Core A) is the engine behind the innovative, impactful research enterprise of Penn CFAR, a collaboration of the University of Pennsylvania, Children's Hospital of Philadelphia, and Wistar Institute. In the current cycle, CFAR investigators have made high impact discoveries in AIDS priority areas including HIV Cure, with funding of a Martin Delaney Collaboratory; the nature of & immune control within lymphoid reservoirs; exciting new vaccine platforms and models; HIV co-infections and comorbidities; multidimensional approaches to improve engagement across the HIV prevention and care continuum; and other key topics. Core A drives the CFAR strategic planning process, provides scientific leadership to identify and launch new research directions, and oversees the establishment and activities of its Scientific Working Groups. Core A oversees CFAR's seven Shared Resource Cores; its Developmental Core; its educational, mentoring, outreach and partnering activities; and initiatives to further enhance strong ties to the campus, Philadelphia community, and local, national and international partners. Core A also provides campus leadership, ensuring institutional support, prioritization for AIDS research and partnerships for faculty recruitment, and communication among CFAR investigators to maintain a collaborative, interactive research community. Core A leadership transitioned 2 years ago, and is led by Drs. Ronald Collman (Director) and Robert Gross (Co- Director), with Dr. Kathleen Brady joining as Core Investigator. Core A works closely with a governing Executive Committee, and an Internal Advisory Board, External Advisory Committee and Community Advisory Board. Core A's aims are to (1) Deploy CFAR resources and activities to stimulate research in current and emerging high priority areas through Scientific Working Groups, interdisciplinary collaborations, Core activities and Developmental projects; (2) Provide administrative leadership to ensure effective communication among all CFAR components and members, lead a robust and inclusive strategic planning process, secure institutional support, and support recruitment of outstanding HIV/AIDS researchers to the campus; (3) Oversee CFAR's Shared Resource Cores to ensure that they enhance research capacity, serve needs of CFAR investigators, introduce new enabling technology and expertise that advance the research agenda and support CFAR SWGs; (4) Ensure sound fiscal management of CFAR Cores, developmental funds and institutional resources; (5) Establish and oversee multidisciplinary educational, mentoring and outreach activities that engage and advance the scientific development of trainees and junior faculty, create partnerships to bring non-HIV investigators into the field, and promote diversity and inclusion in CFAR activities and leadership roles, and; (6) Ensure that CFAR is fully engaged with local communities affected by HIV/AIDS, partners with local organizations, including the Philadelphia Department of Public Health, leverages & contributes to the Inter-CFAR national network, and spearheads robust collaborations & capacity building activities with international partners.