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中文摘要
翻译
摘要-核心A 要求行政核心A促进项目1-2的主要参与者之间的内部互动, 在校内和校外以及NIAID的四个技术支持组件的领导者。这 核心负责总体组织、管理和决策。核心A将提供 向NIAID提交进度报告。数据共享、知识产权的获取/保护以及 机构资源属于其职权范围。该核心将组织沟通、小组会议, 电话会议、介绍和公布数据。及时向NIAID提交所有摘要, PO 1支持的手稿和评论将通过该核心。分配资源以满足 各种计划目标、财政优先次序、资源共享和信息及试剂的责任 传播是一项重要的责任。该核心还将管理与方案有关的差旅预算, 将支持科学顾问委员会(SAB)评估科学进展并考虑临床前工作 未来的临床开发考虑。核心A将监督年度SAB会议, 波士顿,协调涉及NIAID项目工作人员、SAB和共同研究者的旅行和其他后勤工作 出席会议。它将监督一个教育部分,包括一系列与结构有关的研讨会, 免疫原设计、生物材料、疫苗递送和评估的生物物理方法将共同 主持人是瑞赫兹和欧文医生
英文摘要
ABSTRACT - Core A The Administrative Core A is requested to facilitate internal interactions among PIs of Projects 1-2 and leaders of the four technical subcontract components at both on- and off-campus sites and with the NIAID. This core is responsible for the overall organization, management and decision making. Core A will provide progress reports to NIAID. Data sharing, acquisition/protection of intellectual property and involvement of institutional resources are within its purview. This core will organize communications, group meetings, teleconferences, presentations and publication of data. Timely submission to NIAID of all abstracts, manuscripts and reviews supported by the PO1 will be through this core. The allocation of resources to meet various program goals, fiscal prioritization, responsibilities for resource sharing and information and reagent transmission is an important responsibility. This core will also manage a budget for program-related travel and will support a Scientific Advisory Board (SAB) to evaluate scientific progress and consider pre-clinical efforts moving toward future clinical development consideration. Core A will oversee the annual SAB meeting in Boston, coordinating travel and other logistics involving NIAID program staff, SAB and co-investigators attending the meeting. It will oversee an educational component including a seminar series related to structural and biophysical approaches to immunogen design, biomaterials, vaccine delivery and evaluation to be co- hosted by Drs. Reinherz and Irvine.
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A precision tumor neoantigen identification pipeline for cytotoxic T-lymphocyte-based cancer immunotherapies
  • 批准号:
    10581488
  • 项目类别:
  • 资助金额:
    $66.08万
  • 财政年份:
    2022
  • 负责人:
    ELLIS L REINHERZ
  • 依托单位:
A precision tumor neoantigen identification pipeline for cytotoxic T-lymphocyte-based cancer immunotherapies
  • 批准号:
    10332251
  • 项目类别:
  • 资助金额:
    $71.33万
  • 财政年份:
    2022
  • 负责人:
    ELLIS L REINHERZ
  • 依托单位:
Ligand-dependent preTCR function
  • 批准号:
    10225508
  • 项目类别:
  • 资助金额:
    $78.11万
  • 财政年份:
    2020
  • 负责人:
    ELLIS L REINHERZ
  • 依托单位:
Administrative Core
  • 批准号:
    10020597
  • 项目类别:
  • 资助金额:
    $17.1万
  • 财政年份:
    2020
  • 负责人:
    ELLIS L REINHERZ
  • 依托单位:
海外基金