Administrative Core

对人类感觉、知觉、注意力和认知的神经基础的基础和翻译研究 是为临床治疗和干预奠定基础所必需的。已经取得了显著的进展 在发现感知障碍的新的行为和电生理生物标记物方面取得了进展， 注意力、认知和行动。包括精神分裂症、帕金森氏症、自闭症、痴呆症、轻度认知障碍 损伤、创伤性脑损伤、阅读障碍和弱视，仅举几例。这些，以及正常的 老龄化，对大量美国人的健康和生活质量产生了负面影响。发现生物标志物 这类疾病允许早期诊断和干预，转化性研究可能导致 开发新的有效的治疗方法。这项研究反映了该领域的整体进步 CVCN研究人员在第一阶段和第二阶段取得的成就。在第三阶段，我们将继续为 通过支持创造性研究活动和世界级核心，在视觉和认知神经科学领域取得新发现 将促进进一步发现的设施。管理核心提供组织结构，以 将第一阶段和第二阶段实现的研究和基础设施发展目标扩展到第三阶段。 管理核心将促进解决神经机制的研究继续取得成功 人类在正常和无序状态下的感觉、知觉、认知和行动，通过：1) 持续有效运作3个科学/技术核心(技术服务核心；驾驶模拟器核心； 高密度脑电/神经刺激核心)，为CVCN教职员工提供关键任务研究资源 和学生，并使广大当前和未来的用户在 南洋理工大学校园及其他校区；2)继续支持启动的成功竞争试点项目计划 在第一和第二阶段，提供短期支助以及科学指导和职业发展 为有前景的研究建议的申请者提供服务；以及3)开发和积极参与 在印度，两个外联机制(科布雷间理事会和科学交流网络)将为 作为交流科学技术专门知识和传播知识的渠道， 研究结果、想法和最佳实践，在该州内具有类似研究主题的科布雷之间， 这个地区，这个国家。涉及内部审查和外部监督的正式评价进程将是 实施，以确保CVCN的各个组成部分得到很好的整合并有效运作。一个 确保在第三阶段供资期之后持续提供科学/技术核心的计划是 它结合了高效的核心管理、按服务收费的成本回收机制以及 对常设机构资源的承诺。

Basic and translational research into the neural bases of human sensation, perception, attention, and cognition is necessary to lay the foundation for clinical treatments and interventions. Remarkable progress has been made in the discovery of novel behavioral and electrophysiological biomarkers for disorders of perception, attention, cognition, and action. These include schizophrenia, Parkinson's, autism, dementia, mild cognitive impairment, traumatic brain injury, dyslexia, and amblyopia, to name but a few. These, along with normal aging, negatively impact the health and quality of life of a large number of Americans. Discovering biomarkers for such disorders allows early diagnosis and intervention, and translational research may result in the development of novel and effective treatments. Progress in the field as a whole is reflected in the research accomplishments of CVCN researchers in Phases I and II. In Phase III we will continue to contribute to novel discovery in visual and cognitive neuroscience by supporting creative research activity and world-class Core facilities that will potentiate further discovery. The Administrative Core provides the organizational structure to extend into Phase III the research and infrastructure development goals realized in Phases I and II. The Administrative Core will promote the continued success of research addressing the neural mechanisms of human sensation, perception, and cognition, and action, in both normal and disordered states, through: 1) the sustained efficient operation of 3 Scientific/Technical Cores (Technical Services Core; Driving Simulator Core; High-Density EEG/Neurostimulation Core) which provide mission-critical research resources to CVCN faculty and students, and which benefit the scientific activities of a broad array of current and future users on the NDSU campus and beyond; 2) continued support for a successful competitive Pilot Project Program, initiated in Phases I and II, which provides short-term support as well as scientific mentoring and career development services to applicants with promising research proposals; and 3) the development of, and active participation in, two outreach mechanisms (the Inter-COBRE Council and the Scientific Exchange Network) which will serve as conduits for the exchange of scientific and technical expertise and the dissemination of knowledge, research findings, ideas, and best practices, between COBREs with cognate research themes within the state, the region, and the nation. A formal evaluation process involving internal review and external oversight will be implemented to ensure that the various components of the CVCN are well integrated and operate effectively. A plan to ensure the sustained availability of the Scientific/Technical Cores beyond the Phase III funding period is described which combines efficient Core management, a fee-for-service cost recovery mechanism, and the commitment of permanent institutional resources.