National Drug Early Warning System Coordinating Center

项目摘要/摘要 作为回应，我们的团队热情地提交了成为下一个NDEWS协调中心(CC)的建议 转到RFA DA-20-016。CC由Cottler Lab(流行病学)带头，调查人员来自 佛罗里达大学成瘾研究与教育中心(尼克松、戈德伯格、斯特利)，Palamar 纽约大学的实验室和佛罗里达的机器感知和认知机器人实验室 大西洋大学。我们的CC将保持强大的哨兵监视努力，同时扩大我们的早期预警 网络站点，增加了超越滞后的市级数据的前沿指标。我们将延长 NIDA资助的研究人员的工作，同时协调和分析数据，及时和系统地 通知。新的NDEWS CC将致力于将正在进行的工作、先进的方法和 方法，建立并参与科学咨询小组(SAG)，并与所有财团合作 实现这些具体目标的组成部分：1)提供由12个NDEWS站点组成的预警网络和 6个社区流行病学工作组站点，用于对城市、农村和郊区进行持续监测；2) 利用现有和新的关键社区一级指标进行持续监测，以评估#年的趋势 核动力源和已知物质的可用性、使用和后果，在所有地点进行标准化，以便于 跨站点分析；3)采用和利用新的监测方法，以确保及早发现 NPS和新兴毒品趋势的信号，包括来自DanceSafe毒品检查员的数据，Rapid Street 报告(RSR)NPS暴露的头发测试，实施虚拟HealthStreet物质 用户网络，以及开发一种创新的机器学习方法来检测NPS在 通过药品零售商(包括“暗网”)和社交媒体平台进行实时宣传；4)协调 在NIDA、SAG和ELEARY的支持下，对所有收到的监测数据进行标准化指标定义 预警网络专家；促进数据的跨站点可比性；管理质量控制；组织、 协调、汇总数据，并提供组织和后勤支持；5)传播调查结果 通过模仿佛罗里达州毒品相关结果监测和跟踪系统的仪表板快速实现 (Frost)；定期更新和警报的推送通知；网络研讨会；虚拟我们的社区我们的健康城 大会堂会议；以及传统上通过官方报告、同行评议出版物、媒体和年度会议 在CPDD和其他地方报道；6)就以下主题进行实地流行病学调查 紧急危机或需要；7)为企业提供运营、行政和后勤支持； NIDA；以及8)培训NDEWS方法论方面的下一代科学家。 NDEWS具有尚未实现的潜力，有了这笔资金，我们将改变文化，使NDEWS成为 Nida‘s和该领域对美国毒品趋势的首选来源。它将提供基于证据的预防和 干预战略，以最终减少世界各地使用药物的有害影响。

PROJECT SUMMARY/ABSTRACT Our team enthusiastically submits this proposal to be the next NDEWS Coordinating Center (CC) in response to RFA DA-20-016. The CC is spearheaded by the Cottler Lab (Epidemiology), with investigators from University of Florida's Center for Addiction Research & Education (Nixon, Goldberger, Striley), the Palamar Lab at New York University and the Machine Perception and Cognitive Robotics Lab-Barenholtz) at Florida Atlantic University. Our CC will maintain strong sentinel surveillance efforts while expanding our Early Warning Network sites, adding leading edge indicators that extend beyond lagged city-level data. We will extend the work of NIDA-funded researchers, while harmonizing and analyzing data, with timely and systematic notifications. The new NDEWS CC will work to seamlessly transition on-going efforts, advance methods and approaches, establish and engage a Scientific Advisory Group (SAG), and collaborate with all consortium components to accomplish these Specific Aims: 1) Provide an Early Warning Network of 12 NDEWS sites and 6 Community Epidemiology Workgroup sites for ongoing surveillance of urban, rural, and suburban areas; 2) Utilize established and new key community-level indicators for ongoing surveillance to assess trends in availability, use, and consequences of NPS and known substances, standardized across all sites to facilitate cross-site analyses; 3) Incorporate and leverage novel surveillance methods to ensure early detection of signals of NPS and emerging drug trends, including data from DanceSafe “drug checkers,” Rapid Street Reporting (RSR) with hair testing for NPS exposure, the implementation of a virtual HealthStreet substance user network, and development of an innovative machine learning approach to detect emergence of NPS in real-time through drug retailers (including the “darknet”) and social media platforms; 4) Harmonize standardized indicator definitions for all incoming surveillance data with the input of NIDA, the SAG, and Early Warning Network experts; facilitate cross-site comparability of data; manage quality control; organize, coordinate, and summarize data, and provide organizational and logistical support; 5) Disseminate findings quickly via dashboards modeled after Florida Drug-related Outcomes Surveillance and Tracking System (FROST); push notifications for regular updates and alerts; webinars; virtual Our Community Our Health Town Hall meetings; and traditionally through official reports, peer-reviewed publications, media, and annual reporting at CPDD, and elsewhere; 6) Conduct on-the-ground epidemiologic investigations on topics of immediate crisis or need; 7) Provide operational, administrative, and logistical support to the enterprise and NIDA; and 8) Train the next generation of scientists in NDEWS methodology. NDEWS has unrealized potential, and with this funding, we will transform the culture so that NDEWS is NIDA's and the field's go-to source for drug trends in the US. It will provide evidence-based prevention and intervention strategies to eventually reduce the harmful effects of substance use around the world.