Using MVRDL to increase the FDA Vet-LRN sample analysis capacity during animal food/feed emergency events

项目摘要 密西西比州兽医研究和诊断实验室(MVRDL)是一项全方位的服务， AAVLD认证，所有物种，中央参考实验室。我们的工作人员包括10名教职员工。 成员(病理学家、家禽兽医、微生物学家、病毒学家和分子 生物学家)和大约25个工作人员职位。微生物科人员包括： 科长，拥有DVM、硕士和兽医博士学位，拥有25岁以上 有多年的临床和微生物学研究经验，一名技术人员有15年的经验 微生物学经验。这一部分分析了大约3000份材料的样本。 每年有5200多个程序(需氧培养、厌氧培养、抗菌药物 敏感性测试)已完成。 通过我们参与这项合作协议，我们同意参与三个关键 项目区域： (1)参与FDA/Vet-LIRN样品分析。 A.VPO指定的监视任务。 B.动物性食品/药物紧急暴发检测(与国家分析 要求)。 C.大型动物性食品/药品应急事件激增能力(与 国家分析要求)。 (2)通过以下方式为潜在的监管用途提供分析数据： A.使用标准化方法、设备平台和报告方法(标准化 分析工作表和电子结果报告)。 B.参加VPO提供的能力测试和方法培训。 C.应VPO的要求调查消费者报告案例。 D.为实验室实施标准化质量管理体系，如 由VPO确定。 (3)参与小规模方法开发、方法验证和矩阵扩展 由VPO确定的工作。 MVRDL有能力并愿意提供其服务，以增加VPO的能力 在紧急情况下处理增加的样本工作流程。MVRDL致力于执行 这些服务以高效、准确和及时的方式提供并将结果报告给 所需代理机构。

Project Summary The Mississippi Veterinary Research and Diagnostic Laboratory (MVRDL) is a full service, AAVLD accredited, all species, central reference laboratory. Our work force includes 10 faculty members (pathologists, poultry veterinarians, microbiologists, virologists, and molecular biologists) and approximately 25 staff positions. The Microbiology section personnel consist of: a section supervisor with a DVM, MS and a PhD in Veterinary Sciences, with more than 25 years in clinical and research microbiology experience, and one technician with 15 years microbiology experience. The section analyses samples from approximately 3000 accessions per year from which over 5200 procedures (aerobic cultures, anaerobic cultures, antimicrobial susceptibility tests) are completed. Through our participation in this collaborative agreement we agree to participate in the three key project areas: (1) Participation in FDA/Vet-LIRN sample analysis. a. Surveillance assignments as designated by the VPO. b. Animal food/drug emergency outbreak testing (in coordination with State analytical requirements). c. Large-scale animal food/drug emergency event surge capacity (in coordination with State analytical requirements). (2) Providing analytical data for potential regulatory use through: a. Use of standardized methods, equipment platforms, and reporting methods (standardized analytical worksheets and electronic results reporting). b. Participation in proficiency testing and method training provided by the VPO. c. Investigating consumer report cases requested by the VPO. d. Implementation of standardized quality management systems for laboratories as determined by the VPO. (3) Participation in small-scale method development, method validation and matrix extension work as determined by the VPO. MVRDL has the capacity and is willing to offer its' services to increase the capacity of the VPO in handling increased sample workflow during emergencies. MVRDL is committed to performing these services in an efficient, accurate and timely fashion and to reporting the results to the required agency.