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Structural biology and molecular biophysics training program

Structural biology and molecular biophysics training program
结构生物学和分子生物物理学培训计划
批准号:
10192759
负责人:
Ben E. Black
金额:
$39.01万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-07-01 至 2024-06-30

项目摘要

项目成果

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中文摘要
翻译
我们在结构生物学和分子生物学(SBMB)方面的培训计划的中心任务是 利用伊利诺伊大学的巨大资源、杰出的教师和优秀的研究生 宾夕法尼亚州促进和加强结构生物学和分子生物物理学的高级教育。 通过这一培训计划,我们寻求培养一批优秀的学生,他们将在随后提供 在美国生物医学研究的这一核心领域,国家在学术界和工业界都处于领先地位。 我们的计划是为学员量身定做的,不仅是为他们提供深入的技术培训,而且还为他们提供 认识和响应更广泛的生物医学研究工作的需求并在 一种高效、多产和负责任的方式。在美国,没有多少大学能与这项研究相匹配 宾夕法尼亚大学提供的资源。重要的是,大学的所有学校都位于 一个毗连的园区为跨学科的协作交互提供了显著优势。这个 宾夕法尼亚大学在结构生物学和分子方面建立了基础广泛的研究成果。 生物物理学,这对培训计划有很大影响。1927年,该大学获得了一笔捐赠,以 在医学物理学方面建立基础,该基础已经发展为支持一系列技术和能力 包括结构和计算生物物理,高分辨率核磁共振光谱,质谱学, 量热法、电子显微镜和单分子生物物理学--这些方法构成了我们 博士前培训计划。正是在这个强大的技术框架中,培训计划驻留在那里。一个 专注的教员培训人员小组提供了结构的各个子领域的出色覆盖 生物学和分子生物物理学,但其规模允许学员和 运动鞋。培训计划围绕两个为期一年的密集系列会议展开。第一个遗嘱 作为一种工具,不仅向学生介绍SBMB的技术方面,而且还向他们介绍一系列 技能“以及与职业和职业发展直接相关的主题。向所有合格的学生开放,这 一系列会议对生物医学界的影响将远远超出直接得到支持的受训者。 第二系列会议将使学员接触到更激烈的科学发展,并帮助 从初学者过渡到更独立、更高级的研究生。重点将放在 严谨的实验设计和分析。受训人员将主要从优秀的 化学、生物化学和分子生物物理学(BMB)研究生小组的学生。精炼 项目监督、指导和评估机制已经到位。总而言之, 可获得的机构支持与培训员的力量和受训人员的深度相结合 人口确保我们在结构生物学方面的招聘和博士前培训的成功记录 分子生物物理学还将继续。
英文摘要
The central mission of our training program in Structural Biology and Molecular Biophysics (SBMB) is to leverage the immense resources, outstanding faculty, and superb graduate students of the University of Pennsylvania to promote and strengthen advanced education in structural biology and molecular biophysics. Through this training program, we seek to train a cadre of superlative students who will subsequently provide national leadership in both academia and industry in this core area of biomedical research in the United States. Our program is tailored to imbue trainees with not only deep technical training but also to provide the “soft skills” necessary to recognize and respond to the needs of the broader biomedical research effort and to do so in an efficient, productive and responsible way. Not many universities in the United States match the research resources offered by the University of Pennsylvania. Importantly, all schools of the University are located on one contiguous campus providing a significant advantage for collaborative interactions across disciplines. The University of Pennsylvania has established a broadly based research effort in structural biology and molecular biophysics, which significantly impacts the training program. In 1927 the University received an endowment to establish a foundation in medical physics, which has evolved to support a range of technologies and capabilities including structural and computational biophysics, high-resolution NMR spectroscopy, mass spectrometry, calorimetry, electron microscopy and single molecule biophysics - approaches that form the backbone of our pre-doctoral training program. It is in this strong technical framework that the training program resides. A focused group of dedicated faculty trainers provides excellent coverage of the various subfields of structural biology and molecular biophysics but is of a size that permits extensive interaction between trainees and trainers. The training program is structured around two intensive year-long series of meetings. The first will serve as a vehicle to introduce students to not only the technical aspects of SBMB but also to a range of “soft skills” and topics directly relevant to career and professional development. Open to all qualified students, this series of meetings will impact the biomedical community far beyond the trainees that are directly supported. The second series of meetings will expose trainees to more intense scientific development and aid the transition of the novice to the more independent and advanced graduate student. Emphasis will be placed on rigorous experimental design and analysis. Trainees will be drawn largely from the outstanding pool of students in the Chemistry and Biochemistry & Molecular Biophysics (BMB) graduate groups. Refined mechanisms for program oversight, mentoring and evaluation are in place. In summary, the breadth of institutional support available combined with the strength of the trainer faculty and the depth of the trainee population ensures that our record of success for recruitment and pre-doctoral training in structural biology and molecular biophysics will continue.
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