Administrative Core

项目摘要 核心A（行政和生物统计核心）将为4个 建议的项目和核心B，允许对建议的计划进行集中和综合管理 项目一般支助领域包括：与国家基金会一起管理所有赠款行政任务。 卫生研究院和国家心脏，肺和血液研究所，准备和提交所有 所需的报告，预算和会计问题的管理，会议摘要的编写，以及 为出版准备手稿。核心A还将组织项目之间的每周会议 和核心领导人，定期组织项目领导人和核心领导人之间的面对面会议， 组织内部和外部咨询委员会会议。核心A将促进电子通信 通过维护现有的数据交换联合网站，并通过提供多媒体 研究者之间每周会议的沟通。核心A还将作为会计和 合规资源，监测支出和提供预算监督，负责监督所有分部门 合同结算，与供应商进行任何必要的谈判并处理发票。工作人员从 核心A将组织内部和外部咨询委员会的沟通和会议， 传播他们的报告。核心A将在维护所有监管方面提供监督和协助 IACUC和IRB批准。最后，核心A将提供广泛的生物统计学支持， 项目和核心B，包括：数据分析，功率分析，以及新的和正在进行的实验的规划 因为它涉及正在进行的研究和摘要、论文和演示文稿的编写。总的来说， 核心A将提供所有必要的组织、行政和统计支助， 与个别项目和核心的需要，以及作为一个整体的计划项目赠款，以便 确保有效地组织和管理拟议的计划项目。

Project Summary Core A (Administrative and Biostatistics Core) will provide detailed support and resources to each of the 4 proposed projects and to Core B, allowing a centralized and integrated administration of the proposed program project. The general areas of support include: management of all grants administration tasks with the National Institutes of Health and the National Heart, Lung, and Blood Institute, preparation and submission of all required reports, management of budgetary and accounting issues, preparation of abstracts for meetings, and preparation of manuscripts for publication. Core A will also organization the weekly meetings between project and core leaders, organize periodic in person meetings between project leaders and core leaders, and organize meeting of the internal and external advisory boards. Core A will facilitate electronic communication through maintenance of the existing joint website for data exchange and by providing multi-media based communication for the weekly meetings amongst investigators. Core A will also serve as an accounting and compliance resource, monitoring expenditures and providing budgetary oversight, serving to oversee all sub- contract billing, and carrying out any needed negotiation with vendors and processing of invoices. Staff from Core A will organize communication and meetings of both the internal and external advisory boards, and dissemination of their reports. Core A will provide oversight and assistance in maintaining all regulatory approvals (IACUC and IRB approvals). Finally Core A will provide extensive biostatistics support to all of the projects and Core B, including: analysis of data, power analysis, and planning of new and ongoing experiments as it relates to both ongoing studies and the preparation of abstracts, papers, and presentations. In aggregate, Core A will provide all of the necessary organizational, administrative, and statistics support commensurate with the needs of the individual projects and cores, and also the program project grant as a whole, so as to ensure efficient organization and administration of the proposed program project.