Partnership in Implementation Science for Geriatric Mental Health (PRISM)

摘要 拟议的老年心理健康实施科学伙伴关系（PRISM）的总体目标 该项目旨在建立一个中心，整合实施研究，以扩大可持续的、基于证据的 在东亚开展研究能力建设活动的精神卫生干预措施。建议的心理健康 实施研究中心，总部设在泰国，包括中国，将重点减少差距， 治疗和支持社区居住的老年人一般，老年痴呆症的老年人， 特别是相关痴呆症（在本提案中称为痴呆症）。具体目标是：1） 对一种适应文化的“取得成果”执行支助模式进行实证检验， 加强提供循证体育锻炼干预措施，以缩小 在泰国有痴呆症行为和心理症状的老年人（GTO-ThAI）; 2） 建立个人和机构的能力，以实施心理健康干预研究， 泰国和中国; 3）提高泰国和中国决策者利用研究证据的能力 知情决策（EIDM）; 4）建立知识库，供利益攸关方在内部共享学习 每个国家并通过NIMH和其他区域NIMH中心与其他国家合作; 5）与 NIMH计划工作人员，通过科学和计划参与，通过合作协议， 所有项目活动的实施。对老年人的关注是作为泰国公共事务部 健康已经确定了老年人心理健康治疗差距的减少，特别是对于那些 痴呆症及其家庭照顾者，作为国家的一个关键优先事项，由于越来越多的病例， 痴呆症，伴随着泰国迅速增长的老龄化人口。该中心将汇集泰国和 中国跨学科研究人员、政策制定者和非政府组织从业人员与美国研究人员， 具有相互之间以及与研究人员和政策部门成功开展研究合作的历史 参与国的制造商。具体项目目标将分三个阶段实施。成立 第一阶段（第一年）将涉及：在马萨诸塞州波士顿的BWH建立行政核心; 详细的研究方案，供研究地点执行（泰国）; 准备在两国实施创新的心理健康干预解决方案;以及， 联络并探索与NIMH其他区域中心合作的可能性。执行 第二阶段（第二至第四学年）将涉及试点和实施以及扩大研究活动 （泰国）和执行能力建设计划（泰国和中国）。最后阶段（4-5年级） 将致力于评估、数据共享和传播。 1

Abstract The overall goal of the proposed Partnership in Implementation Science for Geriatric Mental Health (PRISM) project is to establish a hub to integrate implementation research for scaling up sustainable, evidence-based mental health interventions with research capacity-building activities for East Asia. The proposed mental health implementation research hub, based in Thailand and including China, will focus on reducing the gap in treatment and support for community-residing older adults in general, and elders with Alzheimer's disease and related dementias (to be referred to as dementia in this proposal) in particular. Specific aims are to: 1) empirically test a culturally adapted Getting-To-Outcomes (GTO) implementation support model aimed at enhancing the delivery of an evidence-based physical exercise intervention for narrowing the treatment gap for older persons with behavioral and psychological symptoms of dementia (BPSD) in Thailand (GTO-ThAI); 2) build individual and institutional capacity for the implementation of mental health intervention research in Thailand and China; 3) improve Thai and Chinese policy makers' capacity for using research for evidence informed decision making (EIDM); 4) develop a knowledge base for shared learning among stakeholders within each country and with other countries through NIMH and other regional NIMH hubs; and, 5) collaborate with NIMH program staff, through scientific and programmatic involvement, through a cooperative agreement for the implementation of all project activities. The focus on older adults was made as the Thai Ministry of Public Health has identified the reduction in the mental health treatment gap for older adults, specifically, for those with dementia and their family caregivers, as a key priority for the nation, due to the rising number of cases of dementia, concomitant with Thailand's rapidly growing aging population. The hub will bring together Thai and Chinese interdisciplinary researchers, policy-makers and NGO practitioners with US-based researchers who have a history of successful research collaborations with each other as well as with researchers and policy makers in the participating countries. Specific project aims will be implemented in three phases. The inception phase (study year 1) will involve: establishing the Administrative Core at BWH, Boston MA; developing a detailed research protocol for implementation at the research sites (Thailand); conducting an assessment of readiness for implementation of innovative mental health intervention solutions in both countries; and, making contacts and exploring possibilities for collaboration with other NIMH regional hubs. The implementation phase (study years 2-4) will involve piloting and conducting the implementation and scale up research activities (Thailand) and implementing the capacity-building plan (Thailand and China). The final stage (study years 4-5) will be devoted to evaluation, data sharing, and dissemination. 1